Results 141 to 150 of about 16,013 (232)

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

open access: yesArthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci   +25 more
wiley   +1 more source

Clinical Decision Support System Based on Hybrid Knowledge Modeling: A Case Study of Chronic Kidney Disease-Mineral and Bone Disorder Treatment. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Ali SI   +9 more
europepmc   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han   +16 more
wiley   +1 more source

Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD). [PDF]

open access: yesCochrane Database Syst Rev
Natale P   +6 more
europepmc   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella   +2 more
wiley   +1 more source

Anti‐Inflammatory Effects of Vicatia thibetica De Boiss. in Rheumatoid Arthritis and Associated Multi‐Pathway Modulation In Vivo

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Vicatia thibetica de Boiss. (VTDB) extracts and fractions were screened for anti‐rheumatoid arthritis activity via UHPLC‐MS, network pharmacology, and CIA rat models. VTDB‐nBuOH stood out, regulating PI3K/Akt, JAK2/STAT3, macrophage polarization, and gut microbiota to relieve joint inflammation, with proteomics verifying its multi‐pathway regulatory ...
Mo‐Zi‐Li Adu   +9 more
wiley   +1 more source

Polyphenols as Natural Therapeutics for Dental Infections and Oral Inflammation: Mechanisms and Clinical Perspectives

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian   +3 more
wiley   +1 more source

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