Molecular pathophysiology of chronic kidney disease-mineral and bone disorder: Focus on the fibroblast growth factor 23-Klotho axis and bone turnover dynamics. [PDF]
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Waitupu A +4 more
europepmc +3 more sources
Chronic Kidney Disease-Mineral and Bone Disorder. [PDF]
Children with chronic kidney disease (CKD) are at high risk of developing mineral and bone disorders (MBD). CKD-MBD comprise altered calcium and phosphate homeostasis, abnormal synthesis and secretion of parathyroid hormone (PTH) and vitamin D and alterations in bone metabolism and function.
Lee WC, Ruan XZ, Chau YY, Chen JB.
europepmc +5 more sources
Adynamic bone disease: Revisited
The bone and mineral disorders form an integral part of the management of a chronic kidney disease (CKD) patient. Amongst various types of bone pathologies in chronic kidney disease-mineral bone disorder (CKD-MBD), the prevalence of adynamic bone disease
Sonia Sharma, Ankur Gupta
doaj +1 more source
Research progress on vascular calcification mechanism for chronic kidney disease [PDF]
Cardiovascular events are the main cause of death in chronic kidney disease(CKD) and end stage renal disease(ESRD).Studies have shown that vascular calcification is an independent risk factor for cardiovascular events.In addition to the prevention of ...
XIONG Hao, YUAN Fang
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Magnesium—A More Important Role in CKD–MBD than We Thought
Chronic kidney disease (CKD) is associated with different complications, including chronic kidney disease–mineral and bone disorder (CKD–MBD), which represents a systemic disorder that involves the presence of different mineral or bone structure ...
Ileana Peride +4 more
doaj +1 more source
Overview of renal osteodystrophy in Brazil: a cross-sectional study [PDF]
Introduction: The epidemiologic profile of renal osteodystrophy (ROD) is changing over time and cross-sectional studies provide essential information to improve care and health policies.
Cinthia E.M. Carbonara +5 more
doaj +1 more source
Pathophysiology of the chronic kidney disease – mineral bone disorder [PDF]
The causes of excess cardiovascular mortality associated with chronic kidney disease (CKD) have been attributed in part to the CKD-mineral bone disorder syndrome (CKD-MBD), wherein, novel cardiovascular risk factors have been identified. The causes of the CKD-MBD are not well known and they will be discussed in this reviewThe discovery of WNT ...
Keith A, Hruska +2 more
openaire +2 more sources
Chronic kidney disease mineral and bone disorder in children [PDF]
Childhood and adolescence are crucial times for the development of a healthy skeletal and cardiovascular system. Disordered mineral and bone metabolism accompany chronic kidney disease (CKD) and present significant obstacles to optimal bone strength, final adult height, and cardiovascular health.
Bakkaloglu, SEVCAN AZİME +2 more
openaire +3 more sources
Management of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)
Chronic kidney disease (CKD) is still a burden on worldwide health issues affecting about 11-13% of the general population. Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a common complication in CKD, which occurs early in the disease, and
Pringgodigdo Nugroho
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Paricalcitol in management of chronic kidney disease–mineral and bone disorder
Mineral and bone disorders in chronic kidney disease (CKD) is a systemic disorder of mineral and bone metabolism due to CKD manifested by either one or a combination of the following: abnormalities of calcium, phosphorus, PTH, or vitamin D metabolism ...
A. K. Eremkina, M. G. Mokrysheva
doaj +1 more source

