Results 31 to 40 of about 16,013 (232)

Mineral and bone disorders secondary to chronic kidney disease (renal osteodystrophy)

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2015
Chronic kidney disease (CKD) in paediatric population gives rise to complex of diseases that is known as chronic kidney disease-mineral and bone disorder (CKD-MBD), which mainly involves the calcium and bone metabolism.
Alphonsus N. Onyiriuka   +7 more
doaj   +1 more source

Recent advances in understanding and managing secondary hyperparathyroidism in chronic kidney disease [version 1; peer review: 3 approved]

open access: yesF1000Research, 2020
Secondary hyperparathyroidism is a complex pathology that develops as chronic kidney disease progresses. The retention of phosphorus and the reductions in calcium and vitamin D levels stimulate the synthesis and secretion of parathyroid hormone as well ...
María E. Rodríguez-Ortiz   +1 more
doaj   +1 more source

Radiographic manifestations of abnormal bone and mineral metabolism in end‐stage renal disease

open access: yesClinical Case Reports, 2019
Key Clinical Message Chronic kidney disease‐mineral and bone disorder (CKD‐MBD) refers to a broader clinical syndrome that develops as a systemic disorder due to CKD, manifested by abnormalities in bone and mineral metabolism and/or extraskeletal ...
Abhilash Koratala   +2 more
doaj   +1 more source

Bone Histo-Morphology in Chronic Kidney Disease Mineral Bone Disorder [PDF]

open access: yesIndian Journal of Hematology and Blood Transfusion, 2016
Chronic Kidney Disease-Mineral Bone Disorder(CKD-MBD) is a systemic disorder of the mineral and bone metabolism seen in patients with Chronic Kidney Disease(CKD). It is manifested by either one or a combination of the following: (a) Abnormalities of calcium, phosphorus, PTH, or vitamin D metabolism.
Khuraijam Bembem   +4 more
openaire   +2 more sources

New triple therapy for the diagnosis of CKD-MBD: a cross-sectional study in Shanxi province

open access: yesBMJ Open
Objectives To seek a triple combination of biomarkers for early diagnosis of chronic kidney disease-mineral and bone metabolic disorder and to explore the diagnostic efficacy of β2-microglobulin, parathyroid hormone and blood urea nitrogen in chronic ...
Yun Zhou   +9 more
doaj   +1 more source

A novel fluorescent probe-based flow cytometric assay for mineral-containing nanoparticles in serum

open access: yesScientific Reports, 2017
Calciprotein particles, nanoscale aggregates of insoluble mineral and binding proteins, have emerged as potential mediators of phosphate toxicity in patients with Chronic Kidney Disease.
Edward R. Smith   +6 more
doaj   +1 more source

Bisphosphonates to reduce bone fractures in stage 3B+ chronic kidney disease: a propensity score-matched cohort study

open access: yesHealth Technology Assessment, 2021
Background: Bisphosphonates are contraindicated in patients with stage 4+ chronic kidney disease. However, they are widely used to prevent fragility fractures in stage 3 chronic kidney disease, despite a lack of good-quality data on their effects ...
Danielle E Robinson   +13 more
doaj   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei   +9 more
wiley   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

Chronic Kidney Disease—Mineral and Bone Disorder (CKD-MBD), from Bench to Bedside

open access: yesKidney and Dialysis, 2023
Chronic kidney disease—mineral and bone disorder (CKD-MBD) is a systemic disorder that increases the risk of morbidity and mortality in dialysis patients.
Kosaku Nitta   +4 more
doaj   +1 more source

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