Results 181 to 190 of about 95,190 (307)

P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders

Medicine Bulletin, EarlyView.
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley   +1 more source

Isozyme distribution of hexokinase, phosphofructokinase and pyruvate kinase in lymphocytes from patients with chronic lymphocytic leukemia [PDF]

, 1982
Rob J. Kraaijenhagen, G C de Gast, M.C.M. van der Heijden, Marianne Streefkerk, F.H.J. Gmelig-Meyling, Gert Rijksen, G. E. J. Staal   +6 more
openalex   +1 more source

Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation

Med Research, EarlyView.
Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin, Mingjun Lu, Jingwei Guo, Chenyang Wang, Teng Ma   +4 more
wiley   +1 more source

Pirtobrutinib in Chronic Lymphocytic Leukemia: Navigating Resistance and the Personalisation of BTK-Targeted Therapy. [PDF]

Cancers (Basel)
Molica S, Allsup D.
europepmc   +1 more source

Rearrangement and expression of T cell antigen receptor genes in B cell chronic lymphocytic leukemia [PDF]

, 1988
JD Norton, J Pattinson, A. V. Hoffbrand, H Jani, JC Yaxley, Brian Leber   +5 more
openalex   +1 more source

Chronic Lymphocytic Leukemia

CA: A Cancer Journal for Clinicians, 1989
openaire   +3 more sources

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

Medicinal Research Reviews, EarlyView.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg, Tracie Widjaja, Adriaan P. IJzerman, Daan van der Es   +3 more
wiley   +1 more source

Real-world cardiovascular risks of ibrutinib in chronic lymphocytic leukemia: a retrospective study. [PDF]

Front Oncol
Ivanovic J, Otasevic V, Markovic K, Vukovic V, Bibic T, Tomic Vujovic K, Kozarac S, Vladicic Masic J, Milic N, Kulic J, Antic D.   +10 more
europepmc   +1 more source

Decreased actin content of lymphocytes from patients with chronic lymphocytic leukemia [PDF]

, 1982
R Stark, LF Liebes, D Nevrla, M Conklyn, R Silber   +4 more
openalex   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

Medicinal Research Reviews, EarlyView.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti   +2 more
wiley   +1 more source