Results 11 to 20 of about 48,138 (255)

Emerging Therapeutic Options for Chronic Pruritus [PDF]

open access: yesAmerican Journal of Clinical Dermatology, 2020
Chronic pruritus, defined as an unpleasant sensation resulting in a need to scratch that lasts more than 6 weeks, is a prevalent and bothersome symptom associated with both cutaneous and systemic conditions. Due to complex pathogenesis and profuse contributing factors, chronic pruritus therapy remains challenging.
Radomir Reszke   +2 more
openaire   +3 more sources

The Neuromodulatory Effect of Antipruritic Treatment of Chronic Prurigo

open access: yesDermatology and Therapy, 2019
Chronic prurigo is an extremely severe pruritic skin disease which presents with multiple, hyperkeratotic and erosive papules, nodules and/or plaques.
Claudia Zeidler   +2 more
doaj   +1 more source

Hand Pruritus: Clinical Profile, Functional Impairment and Disease-related Burden in a Prospective Cohort Study of 395 Patients

open access: yesActa Dermato-Venereologica, 2021
Human hands are complex structures essential for a variety of functions in everyday life. This study prospectively investigated the clinical features of hand pruritus and the resulting functional impairment and disease-related burden in 395 patients with
Teresa Gabriele Nau   +4 more
doaj   +1 more source

Chronic Pruritus: Clinics and Treatment [PDF]

open access: yesAnnals of Dermatology, 2011
Chronic pruritus, one of the main symptoms in dermatology, is often intractable and has a high impact on patient's quality of life. Beyond dermatologic disorders, chronic pruritus is associated with systemic, neurologic as well as psychologic diseases.
Sonja, Grundmann, Sonja, Ständer
openaire   +2 more sources

Pruritus in Autoimmune and Inflammatory Dermatoses

open access: yesFrontiers in Immunology, 2019
Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease ...
Claudia Zeidler   +7 more
doaj   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Analysis of 325 Patients with Chronic Nodular Prurigo: Clinics, Burden of Disease and Course of Treatment

open access: yesActa Dermato-Venereologica, 2020
Chronic nodular prurigo presents with multiple pruriginous nodules and severe pruritus. This study aims to explore the treatment course and regimens in patients with chronic nodular prurigo and to analyse predictive factors contributing to therapeutic ...
Sonja Gründel   +6 more
doaj   +1 more source

Itch in Scabies—What Do We Know?

open access: yesFrontiers in Medicine, 2021
Scabies is a common parasitic skin infestation characterized by severe itch and a heterogenous clinical presentation. Itch, as the cardinal symptom of scabies, is imposing a high burden on affected patients and is often difficult to manage.
Sascha Ständer, Sonja Ständer
doaj   +1 more source

Isatis tinctoria L.-derived Petroleum Ether Extract Mediates Anti-inflammatory Effects via Inhibition of Interleukin-6, Interleukin-33 and Mast Cell Degranulation

open access: yesActa Dermato-Venereologica, 2020
Isatis tinctoria L. (woad) has been used in medicine for centuries and has demonstrated anti-inflammatory effects. However, to date, no well-defined extracts with precise analysis of active substances have been developed.
Tobias Lotts   +6 more
doaj   +1 more source

Interventions for chronic pruritus of unknown origin [PDF]

open access: yesCochrane Database of Systematic Reviews, 2020
Pruritus is a sensation that leads to the desire to scratch; its origin is unknown in 8% to 15% of affected patients. The prevalence of chronic pruritus of unknown origin (CPUO) in individuals with generalised pruritus ranges from 3.6% to 44.5%, with highest prevalence among the elderly.
Andrade, Andrea   +6 more
openaire   +3 more sources

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