Results 21 to 30 of about 47,991 (257)

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Chronic Pruritus: Clinics and Treatment [PDF]

open access: yesAnnals of Dermatology, 2011
Chronic pruritus, one of the main symptoms in dermatology, is often intractable and has a high impact on patient's quality of life. Beyond dermatologic disorders, chronic pruritus is associated with systemic, neurologic as well as psychologic diseases.
Sonja, Grundmann, Sonja, Ständer
openaire   +2 more sources

Mirtazapine for the Treatment of Chronic Pruritus [PDF]

open access: yesMedicines, 2019
Background: Chronic pruritus is a debilitating condition associated with a wide range of dermatologic, systemic and psychogenic etiologies. In patients with chronic pruritus that is refractory to conventional therapy, symptoms can significantly decrease quality of life by contributing to anxiety, sleep disturbances, and in many cases depression. Recent
Raveena Khanna   +4 more
openaire   +3 more sources

Pruritus in Autoimmune and Inflammatory Dermatoses

open access: yesFrontiers in Immunology, 2019
Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease ...
Claudia Zeidler   +7 more
doaj   +1 more source

Analysis of 325 Patients with Chronic Nodular Prurigo: Clinics, Burden of Disease and Course of Treatment

open access: yesActa Dermato-Venereologica, 2020
Chronic nodular prurigo presents with multiple pruriginous nodules and severe pruritus. This study aims to explore the treatment course and regimens in patients with chronic nodular prurigo and to analyse predictive factors contributing to therapeutic ...
Sonja Gründel   +6 more
doaj   +1 more source

Itch in Scabies—What Do We Know?

open access: yesFrontiers in Medicine, 2021
Scabies is a common parasitic skin infestation characterized by severe itch and a heterogenous clinical presentation. Itch, as the cardinal symptom of scabies, is imposing a high burden on affected patients and is often difficult to manage.
Sascha Ständer, Sonja Ständer
doaj   +1 more source

Isatis tinctoria L.-derived Petroleum Ether Extract Mediates Anti-inflammatory Effects via Inhibition of Interleukin-6, Interleukin-33 and Mast Cell Degranulation

open access: yesActa Dermato-Venereologica, 2020
Isatis tinctoria L. (woad) has been used in medicine for centuries and has demonstrated anti-inflammatory effects. However, to date, no well-defined extracts with precise analysis of active substances have been developed.
Tobias Lotts   +6 more
doaj   +1 more source

The PLAUR signaling promotes chronic pruritus. [PDF]

open access: yesFASEB J, 2022
Abstract Chronic itch is a complex sensation of the skin frequently associated with skin diseases, such as atopic dermatitis (AD) and psoriasis. Although Serpin E1 is implicated in chronic itch, its receptor and signaling pathways involved in itch are not known.
Chen W   +11 more
europepmc   +5 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Interventions for chronic pruritus of unknown origin [PDF]

open access: yesCochrane Database of Systematic Reviews, 2020
Pruritus is a sensation that leads to the desire to scratch; its origin is unknown in 8% to 15% of affected patients. The prevalence of chronic pruritus of unknown origin (CPUO) in individuals with generalised pruritus ranges from 3.6% to 44.5%, with highest prevalence among the elderly.
Andrade, Andrea   +6 more
openaire   +3 more sources

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