Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]
, 2003 Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Friedrich, N. +5 more
core +1 more source
Frontiers in Immunology, 2022 Transplantation is a treatment option for patients diagnosed with end-stage organ diseases; however, long-term graft survival is affected by rejection of the transplanted organ by immune and nonimmune responses.
Ranjithkumar Ravichandran +7 more
doaj +1 more source
Proteomics for rejection diagnosis in renal transplant patients: where are we now? [PDF]
, 2016 Rejection is one of the key factors that determine the long-term allograft function and survival in renal transplant patients. Reliable and timely diagnosis is important to treat rejection as early as possible.
Gwinner, Wilfried +3 more
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Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]
, 2020 Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P. +7 more
core +2 more sources
The immunolymphatic theory of chronic rejection [PDF]
Transplantation Proceedings, 1997 Chronic rejection (CR) primarily manifests itself as a progressive obliterative arteriopathy (OA) that most frequently affects medium-sized muscular arteries of vascularized organ allografts. The lack of similar changes in isografts argues strongly for an immunologic basis. The most widely accepted hypothesis proposed to explain CR suggests that direct
J. J. Fung +3 more
openaire +3 more sources
Immunological Aspects Involved in the Degeneration of Cryopreserved Arterial Allografts
Frontiers in Surgery, 2020 Introduction: Cryopreserved arterial allografts have remained an option in patients requiring distal revascularization or associated with vascular infection, in the absence of a valid autogenous saphenous vein.
Mario González-Gay +7 more
doaj +1 more source
Marked mitigation of transplant vascular sclerosis in FasL(gld) (CD95L) mutant recipients. I. The role of alloantibodies in the development of chronic rejection [PDF]
, 1999 Background. In the acute rejection of allografts, the interaction between Fas (CD95) and its ligand (FasL; CD95L) has been shown to be involved in mediating apoptotic cell death.
Aitouche, A +7 more
core +1 more source
B-cell-mediated strategies to fight chronic allograft rejection
Frontiers in Immunology, 2013 Solid organs have been transplanted for decades. Since the improvement in graft selection and in medical and surgical procedures, the likelihood of graft function after one year is now close to 90%.
Ali H Dalloul
doaj +1 more source
Improved surgical technique for the establishment of a murine model of aortic transplantation. [PDF]
, 1998 Aortic allotransplantation is a reliable procedure to study the evolvement of chronic rejection in mice. The progressive nature of this process in mice is characterized by diffuse and concentric myointimal proliferation which is inevitably associated ...
Aitouche, A +6 more
core +1 more source
Pathogenesis of chronic allograft rejection [PDF]
Transplant International, 2003 Chronic allograft nephropathy (CAN) is, besides death of the recipient with graft function, the most common cause of renal transplant loss. It is characterized by loss of function and replacement of tissue by fibrotic material. The pathogenesis is not clear, but seems to be multifactorial and involves events both early and late after transplantation ...
Leendert C. Paul +2 more
openaire +3 more sources