Results 211 to 220 of about 122,977 (290)

Real-Time Quaking-Induced Conversion Assay Applied to the Italian Chronic Wasting Disease Monitoring Plan: Comparison of Classical and Innovative Diagnostic Methods. [PDF]

Pathogens
Mazza M, Favole A, Campia V, Iulini B, Nonno R, Ligios C, Pintus D, Peletto S, Casalone C, Corona C, Bozzetta E, Acutis PL.   +11 more
europepmc   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Chronic Wasting Disease Outbreak in Scandinavia

, 2019
Prion diseases are a family of rare and fatal progressive neurogenerative diseases, characterised by incubation periods up to several months or years, spongiform changes seen as neuronal loss, and no inflammatory response, commonly seen in more frequent viral and bacterial diseases, are visible in blood or cerebrospinal fluid The most known prion ...
openaire   +1 more source

Sensitive, non-invasive detection of chronic wasting disease in wild and captive white-tailed deer using fecal volatile profiling. [PDF]

mSphere
Berna AZ, Pollock TY, Liu Y, Gibison M, Mallikarjun A, Logan J, Otto CM, Odom John AR.   +7 more
europepmc   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Zoonotic Potential of Chronic Wasting Disease after Adaptation in Intermediate Species. [PDF]

Emerg Infect Dis
Barrio T, Benestad SL, Douet JY, Huor A, Lugan S, Aron N, Cassard H, Espinosa JC, Otero A, Bolea R, Torres JM, Andréoletti O.   +11 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Helping to combat chronic wasting disease [PDF]

Fact Sheet, 2003
openaire   +1 more source

Detection of chronic wasting disease prions in soil at an illegal white-tailed deer carcass disposal site. [PDF]

Prion
Grunklee MK, Lichtenberg SS, Lurndahl NA, Schwabenlander MD, Karwan DL, Li EA, Bartz JC, Yuan Q, Larsen PA, Wolf TM.   +9 more
europepmc   +1 more source