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Facts about Wildlife Diseases: Chronic Wasting Disease (CWD)

EDIS
This article is intended to summarize for the general public, and particularly hunters, farmed cervid owners, and landowners, what is currently known about chronic wasting disease (CWD) and its impacts, with information about practices to minimize ...
Bridget B. Baker, Samantha M. Wisely, Anastasia Postowski, Kristen Wilson   +3 more
doaj   +5 more sources

Canine detection of chronic wasting disease (CWD) in laboratory and field settings. [PDF]

Prion, 2023
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy that affects both free-ranging and farmed cervid species, including mule deer, white-tailed deer, and elk (Odocoileus hemionus, Odocoileus virginianus, and Cervus canadensis). Due to the long incubation period and variability of clinical signs, CWD can expand and spread to
Mallikarjun A, Swartz B, Kane SA, Gibison M, Wilson I, Collins A, Moore MB, Charendoff I, Ellis J, Murphy LA, Nichols T, Otto CM.   +11 more
europepmc   +4 more sources

Chronic Wasting Disease (CWD) in Cervids and the Consequences of a Mutable Protein Conformation. [PDF]

ACS Omega, 2022
Chronic wasting disease (CWD) is a prion disease of cervids (deer, elk, moose, etc.). It spreads readily from CWD-contaminated environments and among wild cervids. As of 2022, North American CWD has been found in 29 states, four Canadian provinces and South Korea. The Scandinavian form of CWD originated independently.
Silva CJ.
europepmc   +3 more sources

Intraspecific Contact Among White-Tailed Deer: A Literature Review and Chronic Wasting Disease Case Study. [PDF]

Ecol Evol
We identified five themes underlying research on intraspecific contact among white‐tailed deer: physical touch, social groups, spatial overlap, contact rates, and social networks. We found white‐tailed deer infected with chronic wasting disease exhibited similar rates of intraspecific contact as those without infections.
Wehr NH, Bondo KJ, Rosenberry CS, Stainbrook D, Wallingford BD, Walter WD.   +5 more
europepmc   +2 more sources

Spatial and Temporal Patterns of Prion Gene Variation Are Consistent With a Response to Chronic Wasting Disease-Induced Selection in Wild White-Tailed Deer. [PDF]

Ecol Evol
In this study, we investigated the association between chronic wasting disease (CWD) and variation in the prion protein gene (PRNP) in white‐tailed deer and mule deer sampled in Alberta, Canada between 2014 and 2017. Our results are consistent with CWD selection pressure resulting in increasing frequency of the 96S allele in space and time, indicating ...
Bubac CM, Russell T, McKenzie D, Ball MC, Pybus MJ, Coltman DW, Cullingham CI.   +6 more
europepmc   +2 more sources

Transmission of chronic wasting disease identifies a prion strain causing cachexia and heart infection in hamsters. [PDF]

PLoS ONE, 2011
Chronic wasting disease (CWD) is an emerging prion disease of free-ranging and captive cervids in North America. In this study we established a rodent model for CWD in Syrian golden hamsters that resemble key features of the disease in cervids including ...
Richard A Bessen, Cameron J Robinson, Davis M Seelig, Christopher P Watschke, Diana Lowe, Harold Shearin, Scott Martinka, Alex M Babcock   +7 more
doaj   +1 more source

Experimental Oronasal Transmission of Chronic Wasting Disease Agent from White-Tailed Deer to Suffolk Sheep

Emerging Infectious Diseases, 2021
Chronic wasting disease (CWD) is a fatal prion disease of cervids. We examined host range of CWD by oronasally inoculating Suffolk sheep with brain homogenate from a CWD-positive white-tailed deer.
Eric D. Cassmann, S. Jo Moore, Justin J. Greenlee   +2 more
doaj   +1 more source

County-wide assessments of Illinois white-tailed deer (Odocoileus virginianus) prion protein gene variation using improved primers and potential implications for management

PLoS ONE, 2022
Chronic wasting disease (CWD) is a fatal, highly infectious prion disease that affects captive and wild cervids. Chronic wasting disease is the only known transmissible spongiform encephalopathy affecting free-ranging wildlife. In CWD-positive deer, some
Daniel B. Raudabaugh, Yasuko Ishida, Nicholas J. Haley, William M. Brown, Jan Novakofski, Alfred L. Roca, Nohra E. Mateus-Pinilla   +6 more
doaj   +2 more sources

Distribution of chronic wasting disease (CWD) prions in tissues from experimentally exposed coyotes (Canis latrans). [PDF]

PLoS One
Cervids susceptible to chronic wasting disease (CWD) are sympatric with multiple other animal species that can interact with infectious prions. Several reports have described the susceptibility of other species to CWD prions, or their potential to transport them.
Ho N, McGinn R, Soto P, Spraker TR, Fischer J, VerCauteren K, Nichols T, Morales R.   +7 more
europepmc   +4 more sources

Transmission, Strain Diversity, and Zoonotic Potential of Chronic Wasting Disease

Viruses, 2022
Chronic wasting disease (CWD) is a prion disease affecting several species of captive and free-ranging cervids. In the past few decades, CWD has been spreading uncontrollably, mostly in North America, resulting in a high increase of CWD incidence but ...
Sandra Pritzkow
doaj   +1 more source