Results 11 to 20 of about 5,860,462 (156)

Chronic Wasting Disease: State of the Science [PDF]

Pathogens
Chronic wasting disease (CWD) is a prion disease affecting cervid species, both free-ranging and captive populations. As the geographic range continues to expand and disease prevalence continues to increase, CWD will have an impact on cervid populations,
Jason C. Bartz, Rebeca Benavente, Byron Caughey, Sonja Christensen, Allen Herbst, Edward A. Hoover, Candace K. Mathiason, Debbie McKenzie, Rodrigo Morales, Marc D. Schwabenlander, Daniel P. Walsh, the NC1209: North American Interdisciplinary Chronic Wasting Disease Research Consortium Members   +11 more
doaj   +2 more sources

Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion

Emerging Infectious Diseases, 2017
Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD
Allen Herbst, Camilo Duque Velásquez, Elizabeth Triscott, Judd M. Aiken, Debbie McKenzie   +4 more
doaj   +2 more sources

Zoonotic Potential of Chronic Wasting Disease after Adaptation in Intermediate Species [PDF]

Emerging Infectious Diseases
Chronic wasting disease (CWD) is an emerging disease in Europe. We report an increase in interspecies transmission capacity and zoonotic potential of a moose CWD isolate from Europe after passage in an ovine prion protein–expressing host.
Tomás Barrio, Sylvie L. Benestad, Jean-Yves Douet, Alvina Huor, Séverine Lugan, Naïma Aron, Hervé Cassard, Juan Carlos Espinosa, Alicia Otero, Rosa Bolea, Juan María Torres, Olivier Andréoletti   +11 more
doaj   +2 more sources

Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease [PDF]

Emerging Infectious Diseases, 2012
Chronic wasting disease (CWD) is a fatal, transmissible prion disease that affects captive and free-ranging deer, elk, and moose. Although the zoonotic potential of CWD is considered low, identification of multiple CWD strains and the potential for agent
Samuel E. Saunders, Shannon L. Bartelt-Hunt, Jason C. Bartz   +2 more
doaj   +2 more sources

Susceptibilities of Nonhuman Primates to Chronic Wasting Disease [PDF]

Emerging Infectious Diseases, 2009
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids.
Brent Race, Kimberly D. Meade-White, Michael W. Miller, Kent D. Barbian, Richard Rubenstein, Giuseppe LaFauci, Larisa Cervenakova, Cynthia Favara, Donald Gardner, Dan Long, Michael Parnell, James Striebel, Suzette A. Priola, Anne Ward, Elizabeth S. Williams, Richard Race, Bruce Chesebro   +16 more
doaj   +2 more sources

Detection of Chronic Wasting Disease Prions in Raw, Processed, and Cooked Elk Meat, Texas, USA [PDF]

Emerging Infectious Diseases
We describe chronic wasting disease (CWD) prion detection in raw and cooked meat from a CWD-positive elk. We found limited zoonotic potential in CWD prions from those meat products.
Rebeca Benavente, Fraser Brydon, Francisca Bravo-Risi, Paulina Soto, J. Hunter Reed, Mitch Lockwood, Glenn Telling, Marcelo A. Barria, Rodrigo Morales   +8 more
doaj   +2 more sources

Review on PRNP genetics and susceptibility to chronic wasting disease of Cervidae

Veterinary Research, 2021
To date, chronic wasting disease (CWD) is the most infectious form of prion disease affecting several captive, free ranging and wild cervid species. Responsible for marked population declines in North America, its geographical spread is now becoming a ...
Katayoun Moazami-Goudarzi, Olivier Andréoletti, Jean-Luc Vilotte, Vincent Béringue   +3 more
doaj   +2 more sources

Human Prion Disease and Relative Risk Associated with Chronic Wasting Disease

Emerging Infectious Diseases, 2006
The transmission of the prion disease bovine spongiform encephalopathy (BSE) to humans raises concern about chronic wasting disease (CWD), a prion disease of deer and elk. In 7 Colorado counties with high CWD prevalence, 75% of state hunting licenses are
W. John Pape, Jeri Forster, C. Alan Anderson, Patrick Bosque, Patrick Bosque, Michael Miller   +5 more
doaj   +2 more sources

Prions in Muscles of Cervids with Chronic Wasting Disease, Norway

Emerging Infectious Diseases
Chronic wasting disease (CWD) is an emerging prion disease in Nordic countries and has been detected in reindeer, moose, and red deer since 2016. CWD sporadically detected in moose and red deer in 3 Nordic countries demonstrated pathologic and strain ...
Tram T. Vuong, Federico A. Cazzaniga, Linh Tran, Jørn Våge, Michele Di Bari, Laura Pirisinu, Claudia D’Agostino, Romolo Nonno, Fabio Moda, Sylvie L. Benestad   +9 more
doaj   +2 more sources

Experimental Oronasal Transmission of Chronic Wasting Disease Agent from White-Tailed Deer to Suffolk Sheep

Emerging Infectious Diseases, 2021
Chronic wasting disease (CWD) is a fatal prion disease of cervids. We examined host range of CWD by oronasally inoculating Suffolk sheep with brain homogenate from a CWD-positive white-tailed deer.
Eric D. Cassmann, S. Jo Moore, Justin J. Greenlee   +2 more
doaj   +1 more source