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Monitoring of chronic wasting disease (CWD) (IV)
EFSA Journal, 2023 The European Commission requested an analysis of the Chronic Wasting Disease (CWD) monitoring programme in Norway, Sweden, Finland, Iceland, Estonia, Latvia, Lithuania and Poland (9 January 2017–28 February 2022). Thirteen cases were detected in reindeer,
EFSA Panel on Biological Hazards (BIOHAZ) +24 more
doaj +8 more sources
Susceptibility of Beavers to Chronic Wasting Disease
Biology, 2022 Chronic wasting disease (CWD) is a contagious, fatal, neurodegenerative prion disease of cervids. The expanding geographical range and rising prevalence of CWD are increasing the risk of pathogen transfer and spillover of CWD to non-cervid sympatric ...
Allen Herbst +8 more
doaj +5 more sources
Ticks harbor and excrete chronic wasting disease prions
Scientific Reports, 2023 Chronic wasting disease (CWD) is a fatal neurodegenerative disease caused by infectious prions (PrPCWD) affecting cervids. Circulating PrPCWD in blood may pose a risk for indirect transmission by way of hematophagous ectoparasites acting as mechanical ...
H. N. Inzalaco +7 more
doaj +2 more sources
Chronic wasting disease: Emerging prions and their potential risk. [PDF]
PLoS Pathogens, 2017 Prions cause fatal neurodegenerative diseases in humans and animals by converting the cellular prion protein PrP into aggregation-prone PrP. Chronic wasting disease (CWD) is a prion disease or transmissible spongiform encephalopathy (TSE) of free-ranging
Samia Hannaoui +2 more
doaj +4 more sources
Horizontal Transmission of Chronic Wasting Disease in Reindeer [PDF]
Emerging Infectious Diseases, 2016 We challenged reindeer by the intracranial route with the agent of chronic wasting disease sourced from white-tailed deer, mule deer, or elk and tested for horizontal transmission to naive reindeer.
S. Jo Moore +7 more
doaj +3 more sources
Frontiers in Veterinary Science, 2022 Chronic wasting disease (CWD) is a deleterious brain proteinopathy caused by a pathogenic form of prion protein (PrPSc), which is converted from a benign form of prion protein (PrPC) encoded by the prion protein gene (PRNP).
In-Soon Roh +11 more
doaj +1 more source
Mouse models of chronic wasting disease: A review
Frontiers in Virology, 2023 Animal models are essential tools for investigating and understanding complex prion diseases like chronic wasting disease (CWD), an infectious prion disease of cervids (elk, deer, moose, and reindeer). Over the past several decades, numerous mouse models
Makayla Cook +2 more
doaj +1 more source
Evolutionary Applications, 2020 Identifying the sources of ongoing and novel disease outbreaks is critical for understanding the diffusion of epizootic diseases. Identifying infection sources is difficult when few physical differences separate individuals with different origins ...
William L. Miller, W. David Walter
doaj +1 more source
Prion protein polymorphisms affect chronic wasting disease progression. [PDF]
PLoS ONE, 2011 Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection.
Chad J Johnson +6 more
doaj +1 more source
Gene-Edited Cell Models to Study Chronic Wasting Disease
Viruses, 2022 Prion diseases are fatal infectious neurodegenerative disorders affecting both humans and animals. They are caused by the misfolded isoform of the cellular prion protein (PrPC), PrPSc, and currently no options exist to prevent or cure prion diseases ...
Simrika Thapa +5 more
doaj +1 more source