Results 31 to 40 of about 1,498,287 (280)
Acta virologica, 2011 Chronic wasting disease (CWD) is a prion disease of free-ranging and farmed ungulates (deer, elk, and moose) in North America and South Korea. First described by the late E.S. Williams and colleagues in northern Colorado and southern Wyoming in the 1970s, CWD has increased tremendously both in numerical and geographical distribution, reaching ...
Sabine, Gilch +5 more
openaire +4 more sources
Evolutionary Applications, 2020 Identifying the sources of ongoing and novel disease outbreaks is critical for understanding the diffusion of epizootic diseases. Identifying infection sources is difficult when few physical differences separate individuals with different origins ...
William L. Miller, W. David Walter
doaj +1 more source
Prion protein polymorphisms affect chronic wasting disease progression. [PDF]
PLoS ONE, 2011 Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection.
Chad J Johnson +6 more
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Prion, 2012 Transmissible spongiform encephalopathies (prion diseases) in animals may be associated with a zoonotic risk potential for humans as shown by the occurrence of variant Creutzfeldt-Jakob disease in the wake of the bovine spongiform encephalopathy epidemic.
Daus, Martin L., Beekes, Michael
openaire +3 more sources
The bile duct ligated rat : a relevant model to study muscle mass loss in cirrhosis [PDF]
, 2016 Muscle mass loss and hepatic encephalopathy (complex neuropsychiatric disorder) are serious complications of chronic liver disease (cirrhosis) which impact negatively on clinical outcome and quality of life and increase mortality.
Bosoi, Cristina R. +7 more
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Horizontal Transmission of Chronic Wasting Disease in Reindeer
Emerging Infectious Diseases, 2016 We challenged reindeer by the intracranial route with the agent of chronic wasting disease sourced from white-tailed deer, mule deer, or elk and tested for horizontal transmission to naive reindeer.
S. Jo Moore +7 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Chronic wasting disease (CWD) is a highly contagious disease caused by prions that affects several cervid species and is relentlessly spreading across North America. Very recently, CWD was detected for the first time in Europe. In this study,
R. Nonno +15 more
semanticscholar +1 more source
Chronic hyponatremia in a patient with renal salt wasting and without cerebral disease: relationship between RSW, risk of fractures and cognitive impairment [PDF]
, 2018 Renal salt wasting syndrome (RSW) is defined as a renal loss of sodium leading to hyponatremia and a decrease in extracellular fluid volume (ECV). Differentiation of this disorder from the syndrome of inappropriate antidiuretic hormone secretion (SIADH),
Della Corte V. +3 more
core +1 more source
Gene-Edited Cell Models to Study Chronic Wasting Disease
Viruses, 2022 Prion diseases are fatal infectious neurodegenerative disorders affecting both humans and animals. They are caused by the misfolded isoform of the cellular prion protein (PrPC), PrPSc, and currently no options exist to prevent or cure prion diseases ...
Simrika Thapa +5 more
doaj +1 more source
ACT-ONE - ACTION at last on cancer cachexia by adapting a novel action beta-blocker [PDF]
, 2016 Novel action beta-blockers combine many different pharmacological effects. The espindolol exhibits effects through β and central 5-HT1α receptors to demonstrate pro-anabolic, anti-catabolic, and appetite-stimulating actions.
Lainscak, Mitja, LAVIANO, Alessandro
core +1 more source