Results 51 to 60 of about 1,498,287 (280)

Invariant algebraic surfaces of a chronic wasting disease model

上海师范大学学报. 自然科学版, 2021
In this paper we study a chronic wasting disease (CWD) model of three dimensional ordinary differential equations. We use the method of characteristic curves to give a complete classification of this system with invariant algebraic surfaces. In addition,
YANG Yang, XIE Feng
doaj   +1 more source

Susceptibilities of Nonhuman Primates to Chronic Wasting Disease

Emerging Infectious Diseases, 2009
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids.
Brent Race, Kimberly D. Meade-White, Michael W. Miller, Kent D. Barbian, Richard Rubenstein, Giuseppe LaFauci, Larisa Cervenakova, Cynthia Favara, Donald Gardner, Dan Long, Michael Parnell, James Striebel, Suzette A. Priola, Anne Ward, Elizabeth S. Williams, Richard Race, Bruce Chesebro   +16 more
doaj   +1 more source

Spatiotemporal epizootiology of chronic wasting disease in Wisconsin deer

Ecosphere, 2023
Chronic wasting disease (CWD) is a fatal neurological disease of cervids caused by a misfolded protein with no vaccines or other cures to prevent infection and death.
Michael D. Samuel
doaj   +1 more source

The demographic pattern of infection with chronic wasting disease in reindeer at an early epidemic stage

Ecosphere, 2019
Infection patterns linked to age and sex are crucial to predict the population dynamic effects of diseases in long-lived species. How such demographic patterns of infection arise is often multifactorial, although the cause is commonly seen as a ...
A. Mysterud, K. Madslien, H. Viljugrein, T. Vikøren, R. Andersen, M. E. Güere, S. Benestad, P. Hopp, O. Strand, B. Ytrehus, K. Røed, C. Rolandsen, Jørn Våge   +12 more
semanticscholar   +1 more source

Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk [PDF]

, 2019
BACKGROUND: Muscle wasting from chronic kidney disease (CKD) or from defective insulin signalling results in morbidity and, ultimately, mortality. We have identified an endogenous mediator of insulin resistance, signal regulatory protein alpha (SIRPα ...
Dong, Jiangling, Garibotto, Giacomo, Hruska, Keith, Hu, Zhaoyong, Mitch, William E, Thomas, Sandhya S, Verzola, Daniela, Wu, Jiao   +7 more
core   +2 more sources

Prion seeding activity in DNA extractions: implications for laboratory biosafety

Prion
Infectious prions (PrPSc) are largely resistant to proteolytic digestion, including proteinase K (PK) digestion. While nucleic acid extracts are generally considered non-infectious from a classical microbiology context (i.e.
Sarah C. Gresch, Tamara Morrill, Maddy Ellis-Cramer, Maria Arifin, Lexi E. Frank, Jason C. Bartz, Marc D. Schwabenlander, Tiffany M. Wolf, Gordon B. Mitchell, Jiewen Guan, Peter A. Larsen   +10 more
doaj   +1 more source

Cellular interplay in skeletal muscle regeneration and wasting: insights from animal models

Journal of Cachexia, Sarcopenia and Muscle, 2023
Skeletal muscle wasting, whether related to physiological ageing, muscle disuse or to an underlying chronic disease, is a key determinant to quality of life and mortality.
Pauline Henrot, Léo Blervaque, Isabelle Dupin, Maéva Zysman, Pauline Esteves, Fares Gouzi, Maurice Hayot, Pascal Pomiès, Patrick Berger   +8 more
doaj   +1 more source

Incidence of WHO stage 3 and 4 conditions following initiation of Anti-Retroviral Therapy in resource limited settings [PDF]

, 2012
To determine the incidence of WHO clinical stage 3 and 4 conditions during early anti-retroviral therapy (ART) in resource limited settings (RLS)
A d’Arminio Monforte, A Miranda, Andrea J. Curtis, AS Walker, B Castelnuovo, B Ledergerber, Catherine S. Marshall, CE Gonzalez, Daniel P. O’Brien, DJ Sloan, DR Hoover, Esther C. Casas, J Abadi, J Mermin, Jane Greig, JE Golub, JE Kaplan, JF Etard, Julian H. Elliot, K Buchacz, Leslie Shanks, M-L Newell, Marcio Silveria Da Fonseca, NJ Ives, Philipp Du Cros, R Zachariah, SD Lawn, Sten H. Vermund, Tim Spelman, VO Kasprowicz, W Manosuthi   +30 more
core   +3 more sources

The ecology of chronic wasting disease in wildlife

Biological Reviews of The Cambridge Philosophical Society, 2019
Prions are misfolded infectious proteins responsible for a group of fatal neurodegenerative diseases termed transmissible spongiform encephalopathy or prion diseases. Chronic Wasting Disease (CWD) is the prion disease with the highest spillover potential,
L. Escobar, S. Pritzkow, Steven N. Winter, Daniel A. Grear, M. Kirchgessner, Ernesto Dominguez-Villegas, G. Machado, A. Townsend Peterson, C. Soto   +8 more
semanticscholar   +1 more source

Prevalence and associated factors of protein- energy wasting among patients with chronic kidney disease at Mulago hospital, Kampala-Uganda: a cross-sectional study

BMC Nephrology, 2018
Background Chronic kidney disease (CKD) is global health concern and priority. It is the 12th leading cause of death worldwide. Protein Energy Wasting occurs in 20–25% of patients with chronic kidney disease and can lead to a high morbidity and mortality
Lydia Namuyimbwa, Collins Atuheire, Joel Okullo, Robert Kalyesubula   +3 more
doaj   +1 more source