Exploring metabolic dysfunction in chronic kidney disease [PDF]
, 2012 Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk ...
Slee, Adrian D.
core +2 more sources
Chronic wasting disease prions in mule deer interdigital glands.
PLoS ONE, 2022 Chronic wasting disease (CWD) is a geographically expanding, fatal neurodegenerative disease in cervids. The disease can be transmitted directly (animal-animal) or indirectly via infectious prions shed into the environment.
Anthony Ness +10 more
doaj +2 more sources
Muscle Wasting in Chronic Kidney Disease: Mechanism and Clinical Implications—A Narrative Review
International Journal of Molecular Sciences, 2022 Muscle wasting, known to develop in patients with chronic kidney disease (CKD), is a deleterious consequence of numerous complications associated with deteriorated renal function.
Tsai-Chin Cheng +3 more
semanticscholar +1 more source
PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]
, 2002 Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C. +6 more
core +2 more sources
Hunting strategies to increase detection of chronic wasting disease in cervids
Nature Communications, 2020 The successful mitigation of emerging wildlife diseases may involve controversial host culling. For livestock, ‘preemptive host culling’ is an accepted practice involving the removal of herds with known contact to infected populations.
A. Mysterud +8 more
semanticscholar +1 more source
Biomarkers of systemic inflammation and growth in early infancy are associated with stunting in young Tanzanian children [PDF]
, 2018 Stunting can afflict up to one-third of children in resource-constrained countries. We hypothesized that low-grade systemic inflammation (defined as elevations in serum C-reactive protein or alpha-1-acid glycoprotein) in infancy suppresses the growth ...
Aboud, Said +9 more
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Exposure Risk of Chronic Wasting Disease in Humans
Viruses, 2020 The majority of human prion diseases are sporadic, but acquired disease can occur, as seen with variant Creutzfeldt–Jakob disease (vCJD) following consumption of bovine spongiform encephalopathy (BSE).
Satish K. Nemani +4 more
doaj +1 more source
Large animal models for chronic wasting disease [PDF]
Cell and Tissue Research, 2022 Chronic wasting disease (CWD) is a fatal neurodegenerative prion disease of cervid species including deer, elk, moose and reindeer. The disease has shown both geographic and species expansion since its discovery in the late 1960's and is now recognized in captive and free-ranging cervid populations in North America, Asia and Europe.
openaire +2 more sources
The impact of senescence on muscle wasting in chronic kidney disease
Journal of Cachexia, Sarcopenia and Muscle, 2022 Muscle wasting is a common complication of chronic kidney disease (CKD) that is associated with higher mortality. Although the mechanisms of myofibre loss in CKD has been widely studied, the contribution of muscle precursor cell (MPC) senescence remains ...
Ying Huang +10 more
semanticscholar +1 more source
Novel treatment strategies for chronic kidney disease: insights from the animal kingdom [PDF]
, 2018 Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these ...
Arnold, Walter +7 more
core +1 more source