Results 21 to 30 of about 1,498,287 (280)
Veterinary Pathology, 2005 Chronic wasting disease (CWD) is a unique transmissible spongiform encephalopathy (TSE) of mule deer ( Odocoileus hemionus), white-tailed deer ( O. virginianus), and Rocky Mountain elk ( Cervus elaphus nelsoni). The natural history of CWD is incompletely understood, but it differs from scrapie and bovine spongiform encephalopathy (BSE) by virtue of ...
openaire +4 more sources
Novel Prion Strain as Cause of Chronic Wasting Disease in a Moose, Finland
Emerging Infectious Diseases, 2023 Our previous studies using gene-targeted mouse models of chronic wasting disease (CWD) demonstrated that Norway and North America cervids are infected with distinct prion strains that respond differently to naturally occurring amino acid variation at ...
Julianna L. Sun +9 more
semanticscholar +1 more source
Chronic wasting disease in Europe: new strains on the horizon
Acta Veterinaria Scandinavica, 2021 Prion diseases are fatal neurodegenerative disorders with known natural occurrence in humans and a few other mammalian species. The diseases are experimentally transmissible, and the agent is derived from the host-encoded cellular prion protein (PrP C ),
M. Tranulis +8 more
semanticscholar +1 more source
The economic costs of chronic wasting disease in the United States
PLoS ONE, 2022 Cervids are economically important to a wide range of stakeholders and rights holders in the United States. The continued expansion of chronic wasting disease (CWD), a fatal neurodegenerative disease affecting wild and farmed cervids, poses a direct and ...
S. J. Chiavacci
semanticscholar +1 more source
Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis
International Journal of Molecular Sciences, 2021 Chronic wasting disease (CWD) is a prion disease found in both free-ranging and farmed cervids. Susceptibility of these animals to CWD is governed by various exogenous and endogenous factors.
M. Arifin +5 more
semanticscholar +1 more source
Journal of Infectious Diseases, 2021 Chronic wasting disease (CWD) is the transmissible spongiform encephalopathy or prion disease affecting cervids. In 2016, the first cases of CWD were reported in Europe in Norwegian wild reindeer and moose.
J. Wadsworth +18 more
semanticscholar +1 more source
Chronic wasting disease: a cervid prion infection looming to spillover
Veterinary Research, 2021 The spread of chronic wasting disease (CWD) during the last six decades has resulted in cervid populations of North America where CWD has become enzootic.
Alicia Otero +3 more
semanticscholar +1 more source
Review on PRNP genetics and susceptibility to chronic wasting disease of Cervidae
Veterinary Research, 2021 To date, chronic wasting disease (CWD) is the most infectious form of prion disease affecting several captive, free ranging and wild cervid species. Responsible for marked population declines in North America, its geographical spread is now becoming a ...
K. Moazami-Goudarzi +3 more
semanticscholar +1 more source
First Detection of Chronic Wasting Disease in Moose (Alces alces) in Sweden
Journal of Wildlife Diseases, 2021 : We report the first detection of chronic wasting disease (CWD) in Sweden, in three old female moose (Alces alces). Prions (PrPCWD) were detected in brain but not in lymph nodes. The findings are similar to previously described CWD cases in old moose in
E. Ågren +9 more
semanticscholar +1 more source
Mouse models of chronic wasting disease: A review
Frontiers in Virology, 2023 Animal models are essential tools for investigating and understanding complex prion diseases like chronic wasting disease (CWD), an infectious prion disease of cervids (elk, deer, moose, and reindeer). Over the past several decades, numerous mouse models
Makayla Cook +2 more
doaj +1 more source