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The Zoonotic Potential of Chronic Wasting Disease—A Review
Prion diseases are transmissible neurodegenerative disorders that affect humans and ruminant species consumed by humans. Ruminant prion diseases include bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep and goats and chronic wasting ...
Michael A. Tranulis, Morten Tryland
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A microfluidic biosensor for the diagnosis of chronic wasting disease
Cervids are affected by a neurologic disease that is always fatal to individuals and has population effects. This disease is called chronic wasting disease (CWD) and is caused by a misfolded prion protein.
Sura A. Muhsin +7 more
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Spatiotemporal occupancy patterns of chronic wasting disease
IntroductionChronic wasting disease (CWD) among cervids in Kansas has seen a consistent rise over the years, both in terms of the number of infections and its geographical spread.
Amy J. Davis +6 more
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Chronic Wasting Disease and Potential Transmission to Humans
Chronic wasting disease (CWD) of deer and elk is endemic in a tri-corner area of Colorado, Wyoming, and Nebraska, and new foci of CWD have been detected in other parts of the United States.
Ermias D. Belay +5 more
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Chronic wasting disease: Emerging prions and their potential risk. [PDF]
Samia Hannaoui +2 more
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Chronic wasting disease (CWD) is a deleterious brain proteinopathy caused by a pathogenic form of prion protein (PrPSc), which is converted from a benign form of prion protein (PrPC) encoded by the prion protein gene (PRNP).
In-Soon Roh +11 more
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Until recently, chronic wasting disease of cervids, the only prion disease affecting wildlife, was believed to be geographically concentrated to Colorado and Wyoming within the United States. However, increased surveillance has unveiled several additional pockets of CWD-infected deer and elk in 12 additional states and 2 Canadian provinces.
Sigurdson, C J, Aguzzi, A
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Mouse models of chronic wasting disease: A review
Animal models are essential tools for investigating and understanding complex prion diseases like chronic wasting disease (CWD), an infectious prion disease of cervids (elk, deer, moose, and reindeer). Over the past several decades, numerous mouse models
Makayla Cook +2 more
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Chronic wasting disease (CWD) is a unique transmissible spongiform encephalopathy (TSE) of mule deer ( Odocoileus hemionus), white-tailed deer ( O. virginianus), and Rocky Mountain elk ( Cervus elaphus nelsoni). The natural history of CWD is incompletely understood, but it differs from scrapie and bovine spongiform encephalopathy (BSE) by virtue of ...
openaire +2 more sources
Identifying the sources of ongoing and novel disease outbreaks is critical for understanding the diffusion of epizootic diseases. Identifying infection sources is difficult when few physical differences separate individuals with different origins ...
William L. Miller, W. David Walter
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