Transcriptomic analysis reveals distinct resistant response by physcion and chrysophanol against cucumber powdery mildew [PDF]
Physcion and chrysophanol induce defense responses against powdery mildew in cucumbers. The combination of these two compounds has synergistic interaction against the disease.
Yanping Li +5 more
doaj +3 more sources
Oxalis corniculata L. Ethanol Extract Promotes Fracture Healing: Integrated Omics and Experimental Validation [PDF]
Oxalis corniculata L. ethanol extract (OCEE) showed efficacy in promoting fracture healing. A total of 549 compounds were identified by UHPLC‐Q‐Exactive‐MS/MS, with three key components recognized. OCEE may accelerate fracture healing by regulating TNFα, MMP9, ESR1, TP53, and related signaling pathways. ABSTRACT Oxalis corniculata L.
Jian Zhang +5 more
wiley +2 more sources
Purpose This study aimed to investigate the inhibitory effect of chrysophanol on renal fibrosis and its molecular mechanism.Methods Initially, potential targets of chrysophanol were predicted through network pharmacology analysis, and a protein-protein ...
Neng Bao +7 more
doaj +2 more sources
Multi-omics exploration demonstrated the antidepressant effects of chrysophanol on diabetes-depression comorbidity rats via inflammatory, and neurodegenerative axes [PDF]
The escalating prevalence of diabetes-depression comorbidity (DDC) necessitates novel therapies targeting shared pathophysiological pathways, which needs to decipher the underlying molecular mechanisms.
Xue-jian Hu +3 more
doaj +2 more sources
Anthraquinones From Epicoccum sp., a Fungus Isolated From Gut of Dione juno That Feeds on Passifloras [PDF]
An Epicoccum fungus was isolated from gut of larvae of the butterfly Dione juno juno that feeds intensively on leaves of Passifloras. This fungus produces hydroxyanthraquinones that moderately inhibits growth of some Bacillus that coexist with the fungus in the insect gut, suggesting that it is probably important for microbial embalance in gut flora ...
Jessica Teixeira Dias +5 more
wiley +2 more sources
Emodin and the Anthraquinone Scaffold: Therapeutic Promise and Strategies to Overcome Translational Barriers [PDF]
Emodin, a trihydroxy-methyl anthraquinone abundant in rhubarb, Polygonum species, and other medicinal plants, exemplifies the therapeutic potential and translational complexity of the broader anthraquinone scaffold.
Rositsa Mihaylova +3 more
doaj +2 more sources
Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats [PDF]
Objective(s): This study aimed to investigate the protective effect and underlying mechanism of chrysophanol (CPH) on senile osteoporosis (OP) in rats.
Qing Lu +6 more
doaj +2 more sources
Cancer continues to be a leading cause of death worldwide, highlighting the urgent need for the development of new therapeutic strategies. Chrysophanol, a naturally occurring anthraquinone compound, has demonstrated significant potential in cancer ...
Dehong Liu +8 more
doaj +2 more sources
Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum [PDF]
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao +6 more
wiley +2 more sources
A TD-DFT Study on the Photo-Physicochemical Properties of Chrysophanol from Rheum
As a naturally occurring anthraquinone pigment, chrysophanol (MHAQ) has attracted considerable attention in recent years owing to its efficient photosensitivity under the solar spectrum. Considering the successful use of time-dependent density functional
Dezhan Chen +2 more
exaly +2 more sources

