Results 21 to 30 of about 4,551 (194)

<i>Oxalis corniculata</i> L. Ethanol Extract Promotes Fracture Healing: Integrated Omics and Experimental Validation. [PDF]

Food Sci Nutr
Oxalis corniculata L. ethanol extract (OCEE) showed efficacy in promoting fracture healing. A total of 549 compounds were identified by UHPLC‐Q‐Exactive‐MS/MS, with three key components recognized. OCEE may accelerate fracture healing by regulating TNFα, MMP9, ESR1, TP53, and related signaling pathways. ABSTRACT Oxalis corniculata L.
Zhang J, Zhao X, Long X, Zhang Y, Luo X, Shen W.   +5 more
europepmc   +2 more sources

Anthraquinones From Epicoccum sp., a Fungus Isolated From Gut of Dione juno That Feeds on Passifloras. [PDF]

Chem Biodivers
An Epicoccum fungus was isolated from gut of larvae of the butterfly Dione juno juno that feeds intensively on leaves of Passifloras. This fungus produces hydroxyanthraquinones that moderately inhibits growth of some Bacillus that coexist with the fungus in the insect gut, suggesting that it is probably important for microbial embalance in gut flora ...
Dias JT, Santos AD, Alves MAPMS, de Souza CWO, Pilau EJ, Rodrigues-Filho E.   +5 more
europepmc   +2 more sources

Chrysophanol protects against doxorubicin-induced cardiotoxicity by suppressing cellular PARylation

Acta Pharmaceutica Sinica B, 2019
The clinical application of doxorubicin (DOX) in cancer chemotherapy is limited by its life-threatening cardiotoxic effects. Chrysophanol (CHR), an anthraquinone compound isolated from the rhizome of Rheum palmatum L., is considered to play a broad role ...
Jing Lu, Jingyan Li, Yuehuai Hu, Zhen Guo, Duanping Sun, Panxia Wang, Kaiteng Guo, Dayue Darrel Duan, Si Gao, Jianmin Jiang, Junjian Wang, Peiqing Liu   +11 more
doaj   +3 more sources

Synthesis of antioxidative anthraquinones as potential anticancer agents

Bibechana, 2021
Antioxidant and antibacterial activities of natural anthraquinones namely chrysophanol (1) and emodin (2), and synthesized anthraquinones viz. 2-methylanthraquinone (3), anthraquinone (4), 2-bromoanthraquinone (5), rubiadin (6), chrysophanol diacetate ...
Richa K. Gupta, Ganesh M. S. Thakuri, Gan B Bajracharya, Ram Narayan Jha   +3 more
doaj   +3 more sources

Chrysophanol Attenuates Manifestations of Immune Bowel Diseases by Regulation of Colorectal Cells and T Cells Activation In Vivo

Molecules, 2021
Inflammatory bowel disease (IBD) is an immune disorder that develops due to chronic inflammation in several cells. It is known that colorectal and T cells are mainly involved in the pathogenesis of IBD. Chrysophanol is an anthraquinone family member that
Hyun-Su Lee, Gil-Saeng Jeong
doaj   +1 more source

Multi-Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum. [PDF]

Plant Biotechnol J
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Zhao S, Zong Y, Wang T, Li J, Ye Z, Zhang F, Zhou G.   +6 more
europepmc   +2 more sources

Mutagenicity of islandicin and chrysophanol in the Salmonella/microsome system [PDF]

Applied and Environmental Microbiology, 1980
Chrysophanol and islandicin, two anthraquinones which are structurally related to emodin, were found to be frame-shift mutagens for Salmonella typhimurium strain TA 1537 after metabolic activation.
D F, Liberman, F L, Schaefer, R C, Fink, M, Ramgopal, A C, Ghosh, R, Mulcahy   +5 more
openaire   +2 more sources

Chrysophanol Exerts Anti-inflammatory Activity by Targeting Histone Deacetylase 3 Through the High Mobility Group Protein 1-Nuclear Transcription Factor-Kappa B Signaling Pathway in vivo and in vitro

Frontiers in Bioengineering and Biotechnology, 2021
Chrysophanol (Chr) is the main monomer isolated from Rheum rhabarbarum. This study aimed to identify the potential in vitro and in vivo cytoprotective effects of Chr on lipopolysaccharide (LPS)-triggered acute lung injury (ALI).
Quan Wen, Quan Wen, Ngaikeung Lau, Huandi Weng, Peng Ye, Shaohui Du, Chun Li, Jianping Lv, Hui Li   +8 more
doaj   +1 more source

Construction of chrysophanol loaded nanoparticles with N-octyl-O-sulfate chitosan for enhanced nephroprotective effect.

European Journal of Pharmaceutical Sciences, 2023
Natural occurring anthraquinone like chrysophanol has been studied because of its anti-diabetic, anti-tumor, anti-inflammatory, hepatoprotective and neuroprotective properties.
Qingxue Wei, Fuping Gao, Leiping Gao, Hong Gao, Jian Zhang, Rui Bao, Hang Zhang, Jiapeng Wang, Qiusheng Shen, Mingjia Gu   +9 more
semanticscholar   +1 more source

One-pot Synthesis of N-doped Reduced Graphene Oxide Decorated with Au-Pd@Au Alloy Nanodendrites for Electrochemical Detection of Chrysophanol

International Journal of Electrochemical Science, 2020
We demonstrate for the first time a new one-step effective route for the preparing of N-doped reduced graphene oxide loading with Au-Pd@Au (N-rGO-Au-Pd@Au) alloy nanodendrites. Then the prepared N-rGO-Au-Pd@Au alloy nanodendrites were used to fabricate a
Ling Shi, Ze-Feng Wang, Na Wu, Gao-Zhang Gou, Xian-Lan Chen, Guang-Ming Yang, Wei Liu   +6 more
doaj   +1 more source