Results 51 to 60 of about 4,551 (194)

Chrysophanol Ameliorates Hemin-Induced Oxidative Stress and Endoplasmic Reticulum Stress by Regulating MicroRNA-320-5p/Wnt3a Pathway in HT22 Cells

Oxidative Medicine and Cellular Longevity, 2022
Oxidative stress, endoplasmic reticulum (ER) stress, and neuronal cell apoptosis have been considered as the main pathogenesis factors of brain injury after intracerebral hemorrhage (ICH).
Xu Zhao, Dongge Qiao, D. Guan, Kun Wang, Yinglin Cui   +4 more
semanticscholar   +1 more source

Preparative Isolation of Three Anthraquinones from Rumex japonicus by High-Speed Counter-Current Chromatography

Molecules, 2011
Three anthraquinones—emodin, chrysophanol, and physcion—were successfully purified from the dichloromethane extract of the Chinese medicinal herb Rumex japonicus by high-speed counter-current chromatography (HSCCC).
Shuying Guo, Bo Feng, Ruonan Zhu, Jiankang Ma, Wei Wang   +4 more
doaj   +1 more source

Chrysophanol from the Roots of Kniphofia Insignis and Evaluation of Its Antibacterial Activities

Journal of chemistry, 2022
Sequential extraction of the roots of Kniphofia insignis using cold maceration techniques and column chromatographic separation leads to the isolation of one monomeric anthraquinone, chrysophanol (1).
Asnake Tadesse, Beshir Legas Muhammed, M. Zeleke   +2 more
semanticscholar   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, Volume 7, Issue 2, Page 52-66, June 2026.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages

Frontiers in Pharmacology, 2022
Acute liver failure (ALF) is an unfavorable condition characterized by the rapid loss of liver function and high mortality. Chrysophanol-8-O-glucoside (CPOG) is an anthraquinone derivative isolated from rhubarb. This study aims to evaluate the protective
Tao Wang, Zhuo Lu, Xinhui Qu, Z. Xiong, Ya-Ting Wu, Yong Luo, Ziyao Zhang, Xiao-Jian Han, Caipeng Xie   +8 more
semanticscholar   +1 more source

Root Endophytic Fungi Regulate Changes in Sugar and Medicinal Compositions of Polygonum cuspidatum

Frontiers in Plant Science, 2022
Polygonum cuspidatum Sieb. et Zucc is an important industrial crop because it contains a large amount of medicinal secondary metabolites (such as polydatin, resveratrol, chrysophanol, and emodin).
Rui-Ting Sun, Xiang-Cao Feng, Ze-Zhi Zhang, Nong Zhou, Hai-Dong Feng, Yi-Mei Liu, Abeer Hashem, Al-Bandari Fahad Al-Arjani, Elsayed Fathi Abd_Allah, Qiang-Sheng Wu   +9 more
doaj   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Enhancement of anti-inflammatory activity of Aloe vera adventitious root extracts through the alteration of primary and secondary metabolites via salicylic acid elicitation. [PDF]

PLoS ONE, 2013
Aloe vera (Asphodeloideae) is a medicinal plant in which useful secondary metabolites are plentiful. Among the representative secondary metabolites of Aloe vera are the anthraquinones including aloe emodin and chrysophanol, which are tricyclic aromatic ...
Yun Sun Lee, Hyun Kyoung Ju, Yeon Jeong Kim, Tae-Gyu Lim, Md Romij Uddin, Yeon Bok Kim, Jin Hong Baek, Sung Won Kwon, Ki Won Lee, Hak Soo Seo, Sang Un Park, Tae-Jin Yang   +11 more
doaj   +1 more source

Comparison of Recycled Polypropylene Sourced From Food and Nonfood Applications for Direct Food Contact Use

Packaging Technology and Science, Volume 39, Issue 6, Page 765-778, June 2026.
Utilisation of postconsumer recycled (PCR) plastic for food contact has safety concerns due to the potential presence of unapproved intentionally/non‐intentionally added substances, which can pose health and environmental risks if not removed during recycling.
Khairun Tumu, Keith Vorst, Greg Curtzwiler   +2 more
wiley   +1 more source

Intestinal absorption and first-pass metabolism of polyphenol compounds in rat and their transport dynamics in Caco-2 cells. [PDF]

PLoS ONE, 2012
BACKGROUND: Polyphenols, a group of complex naturally occurring compounds, are widely distributed throughout the plant kingdom and are therefore readily consumed by humans.
Zenghui Teng, Chengjun Yuan, Feng Zhang, Menglei Huan, Weidong Cao, Kangchu Li, Jingyue Yang, Dayong Cao, Siyuan Zhou, Qibing Mei   +9 more
doaj   +1 more source