Results 161 to 170 of about 21,613 (212)
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Biochemical Society Transactions, 2004
Chylomicrons are the ‘orphans’ of the lipoprotein family. Difficulty of measurement has impeded understanding of their metabolism. Plasma concentrations of chylomicrons and chylomicron remnants give no insight into the magnitude of substrate flux through these pathways.
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Chylomicrons are the ‘orphans’ of the lipoprotein family. Difficulty of measurement has impeded understanding of their metabolism. Plasma concentrations of chylomicrons and chylomicron remnants give no insight into the magnitude of substrate flux through these pathways.
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Conversion of chylomicrons into remnants
Atherosclerosis, 1998The turnover of chylomicrons in the blood is the sum of several processes. The native chylomicron is synthesized in the intestine out of available substrates. When the chylomicron enters the circulation exchanges of apolipoproteins with other lipoproteins, it also binds to the vascular endothelium where the chylomicron is lipolyzed by lipoprotein ...
M, Hultin, T, Olivecrona
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Chylomicron and chylomicron remnant metabolism in STZ-induced diabetic rats
Diabetes, 1992The small intestine is an important source of plasma lipoproteins in various diabetic animal models. This increase in intestinally derived lipids originate from diet and/or primary lipid synthesis, and these lipids are transported to the plasma as chylomicrons (CM).The understanding of the metabolism of these triglyceride-rich particles has assumed ...
I, Staprans +3 more
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Characterization of human chylomicrons
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1982Apolipoprotein and lipid composition of differently sized chylomicrons from healthy volunteers was determined. During their intravasal catabolism the chylomicrons lose triacylglycerol and apolipoproteins. Decreasing particle size results in a loss of apolipoprotein C and apolipoprotein E peptides and an increase in apolipoproteins B and A-I, which ...
W, Haberbosch, A, Poli, J, Augustin
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Signposts in the assembly of chylomicrons
Frontiers in Bioscience, 2001Intestinal cells synthesize and secrete chylomicrons in the postprandial state. Synthesis of these particles is defective in abetalipoproteinemia and chylomicron retention disease. Chylomicrons are very large, heterogeneous, lipid-rich particles ranging in diameters from 75 to 450 nm and function to transport dietary fat and fat-soluble vitamins to ...
M M, Hussain +4 more
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Atherosclerosis, 2012
To better understand the postprandial clearance of triglyceride-rich lipoproteins (TRLs) and its relation to the fasting kinetics of TRLs.Two studies were performed on 30 male subjects: a fasting kinetic study to determine the fasting secretion and clearance rates of apolipoprotein B (apoB) 100 and triglycerides in the very low-density lipoprotein 1 ...
Westerbacka Jukka +7 more
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To better understand the postprandial clearance of triglyceride-rich lipoproteins (TRLs) and its relation to the fasting kinetics of TRLs.Two studies were performed on 30 male subjects: a fasting kinetic study to determine the fasting secretion and clearance rates of apolipoprotein B (apoB) 100 and triglycerides in the very low-density lipoprotein 1 ...
Westerbacka Jukka +7 more
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The quantitative separation of chylomicrons and chylomicron remnants by column chromatography
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1987Chylomicrons and chylomicron remnants cannot be separated by classical techniques of ultracentrifugation or gel filtration, since there is a marked overlap of density and size. Chylomicron remnants develop a high negative surface charge during their formation presumably due to surface-oriented free fatty acids.
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Chylomicrons and chylomicron remnants in coronary artery disease: a case-control study
Atherosclerosis, 1987Epidemiologic studies of coronary artery disease have largely overlooked the role of triglyceride-rich lipoproteins circulating in the post-prandial state. We have conducted a case-control study in males which examined fasting plasma lipoproteins and lipoproteins circulating 4 h after ingestion of a test meal containing fat and cholesterol.
L.A. Simons +10 more
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2009
Lycopene, like other lipophilic dietary components, is absorbed from the intestine in chylomicrons. These large, triacylglycerol-rich lipoproteins are metabolized in the blood by removal of some of the triacylglycerol, leaving smaller chylomicron remnants particles that deliver the remaining lipids to the liver.
Kathleen Botham, Elena Bravo
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Lycopene, like other lipophilic dietary components, is absorbed from the intestine in chylomicrons. These large, triacylglycerol-rich lipoproteins are metabolized in the blood by removal of some of the triacylglycerol, leaving smaller chylomicron remnants particles that deliver the remaining lipids to the liver.
Kathleen Botham, Elena Bravo
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