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Chylomicron and chylomicron remnant catabolism
Current Opinion in Lipidology, 1991Hepatic clearance of chylomicrons and chylomicron remnants appears to involve several steps: sequestration in the space of Disse, further lipolytic processing, and receptor-mediated internalization and degradation. The low-density lipoprotein receptor and possibly the low-density lipoprotein receptor-related protein may participate in this process ...
Robert W. Mahley, M Mahmood Hussain
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Effects of VLDL, chylomicrons, and chylomicron remnants on platelet aggregability
Thrombosis Research, 1995Although influences of cholesterol-rich lipoproteins on platelet aggregation are well established, the knowledge of interactions between triglyceride-rich lipoproteins and platelets, in particular in the postprandial state, is limited and controversial.
Orth, Matthias +2 more
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Biochemical Society Transactions, 2004
Chylomicrons are the ‘orphans’ of the lipoprotein family. Difficulty of measurement has impeded understanding of their metabolism. Plasma concentrations of chylomicrons and chylomicron remnants give no insight into the magnitude of substrate flux through these pathways.
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Chylomicrons are the ‘orphans’ of the lipoprotein family. Difficulty of measurement has impeded understanding of their metabolism. Plasma concentrations of chylomicrons and chylomicron remnants give no insight into the magnitude of substrate flux through these pathways.
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Conversion of chylomicrons into remnants
Atherosclerosis, 1998The turnover of chylomicrons in the blood is the sum of several processes. The native chylomicron is synthesized in the intestine out of available substrates. When the chylomicron enters the circulation exchanges of apolipoproteins with other lipoproteins, it also binds to the vascular endothelium where the chylomicron is lipolyzed by lipoprotein ...
M, Hultin, T, Olivecrona
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Chylomicron and chylomicron remnant metabolism in STZ-induced diabetic rats
Diabetes, 1992The small intestine is an important source of plasma lipoproteins in various diabetic animal models. This increase in intestinally derived lipids originate from diet and/or primary lipid synthesis, and these lipids are transported to the plasma as chylomicrons (CM).The understanding of the metabolism of these triglyceride-rich particles has assumed ...
I, Staprans +3 more
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Characterization of human chylomicrons
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1982Apolipoprotein and lipid composition of differently sized chylomicrons from healthy volunteers was determined. During their intravasal catabolism the chylomicrons lose triacylglycerol and apolipoproteins. Decreasing particle size results in a loss of apolipoprotein C and apolipoprotein E peptides and an increase in apolipoproteins B and A-I, which ...
W, Haberbosch, A, Poli, J, Augustin
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