Results 101 to 110 of about 118,118 (316)

Acrylamide Production Using Encapsulated Nitrile Hydratase from \u3cem\u3ePseudonocardia thermophila\u3c/em\u3e in a Sol–gel Matrix [PDF]

, 2014
The cobalt-type nitrile hydratase from Pseudonocardia thermophila JCM 3095 (PtNHase) was successfully encapsulated in tetramethyl orthosilicate sol–gel matrices to produce a PtNHase:sol–gel biomaterial.
Elgren, Timothy E., Holz, Richard C., Kuhn, Misty L., Martinez, Salette, Russell, James T.   +4 more
core   +1 more source

N-terminal proteomics assisted profiling of the unexplored translation initiation landscape in Arabidopsis thaliana [PDF]

, 2017
Proteogenomics is an emerging research field yet lacking a uniform method of analysis. Proteogenomic studies in which N-terminal proteomics and ribosome profiling are combined, suggest that a high number of protein start sites are currently missing in ...
Gevaert, Kris, Jonckheere, Veronique, Martens, Lennart, Ndah, Elvis, Stael, Simon, Sticker, Adriaan, Van Breusegem, Frank, Van Damme, Petra, Willems, Patrick   +8 more
core   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Partial characterization of the digestive proteases and α-amylase of the larvae of the red palm weevil, Rhynchophorus ferrugineus [PDF]

Arthropods, 2020
Activity of digestive enzymes (trypsin, chymotrypsin and α-amylase) in soluble protein extracted from the larval gut of Rhynchophorus ferrugineus was studied using specific substrates and enzyme inhibitors.
Ashraf Oukasha Abd El-latif
doaj  

Toward an Alternative Intrinsic Probe for Spectroscopic Characterization of a Protein [PDF]

, 2010
The intrinsic fluorescent amino acid tryptophan is the unanimous choice for the spectroscopic investigation of proteins. However, several complicacies in the interpretation of tryptophan fluorescence in a protein are inevitable and an alternative ...
Goswami, Nirmal, Makhal, Abhinandan, Pal, Samir Kumar   +2 more
core   +1 more source

Photopharmacology beyond azobenzene photoswitches

Responsive Materials, EarlyView.
Photopharmacology is advancing beyond traditional azobenzene photoswitches by developing new photoresponsive molecules with improved thermal stability, efficiency, and long‐wavelength activation, enhancing their potential for precise biomedical applications.
Huichao Guo, Jinghong Dai, Long Deng, Zhiwei Zhang, He Tian, Junji Zhang   +5 more
wiley   +1 more source

Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State [PDF]

, 2016
The mitochondrial thioredoxin system (NADPH, thioredoxin reductase, thioredoxin) is a major redox regulator. Here we have investigated the redox correlation between this system and the mitochondrial enzyme cyclophilin D.
Bindoli, Alberto, Cali', Tito, Citta, Anna, Folda, Alessandra, Rigobello, MARIA PIA, Scalcon, Valeria, Scutari, Guido, Zonta, Francesco   +7 more
core   +1 more source

A Self‐Assembling Peptide with Nanoparticle‐to‐Fibril Transformation Exhibits Multimodal Antimicrobial Activity through Membrane Disruption and Quorum‐Sensing Inhibition

Small, EarlyView.
A self‐assembling peptide that transforms from nanoparticles into bacterial‐entrapping nanofibrils and targets multi‐drug‐resistant pathogens through a dual mechanism. It disrupts bacterial membranes and strongly inhibits the quorum‐sensing system, a crucial factor in biofilm formation and virulence.
James Mwangi, Demeke Asmamaw, Min Yang, Dawit Adisu Tadese, Brenda B. Michira, Yi Wang, Sheng‐wen Zhou, Gan Wang, Ziyi Wang, Qiu‐Min Lu, Ren Lai   +10 more
wiley   +1 more source

Chymotrypsin C Is a Co-activator of Human Pancreatic Procarboxypeptidases A1 and A2*

Journal of Biological Chemistry, 2010
Human digestive carboxypeptidases CPA1, CPA2, and CPB1 are secreted by the pancreas as inactive proenzymes containing a 94–96-amino acid-long propeptide. Activation of procarboxypeptidases is initiated by proteolytic cleavage at the C-terminal end of the
R. Szmola, M. Bence, A. Carpentieri, A. Szabó, C. Costello, J. Samuelson, M. Sahin-Tóth   +6 more
semanticscholar   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source