Results 21 to 30 of about 57,869 (249)

Protease Inhibitors from Marine Venomous Animals and Their Counterparts in Terrestrial Venomous Animals

Marine Drugs, 2013
The Kunitz-type protease inhibitors are the best-characterized family of serine protease inhibitors, probably due to their abundance in several organisms.
Caroline B. F. Mourão, Elisabeth F. Schwartz   +1 more
doaj   +1 more source

Safety evaluation of a food enzyme containing trypsin, chymotrypsin, elastase and carboxypeptidase from porcine pancreas

EFSA Journal, 2021
The food enzyme is a protease complex, containing trypsin (EC 3.4.21.4), chymotrypsin (EC 3.4.21.1), pancreatic elastase (EC 3.4.21.36) and carboxypeptidase B (EC 3.4.17.2), obtained from porcine pancreas by Neova Technologies Inc.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Claude Lambré, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Ursula Gundert‐Remy, Lieve Herman, Dominique Turck, Karl‐Heinz Engel, Margarita Aguilera‐Gómez, Magdalena Andryszkiewicz, Natalia Kovalkovicova, Yi Liu, Joaquim Maia, Sandra Rainieri, Andrew Chesson   +28 more
doaj   +1 more source

A combined spectroscopic and molecular modeling Study on structure-function-dynamics under chemical modification: Alpha-chymotrypsin with formalin preservative

Frontiers in Chemistry, 2022
Enzyme function can be altered via modification of its amino acid residues, side chains and large-scale domain modifications. Herein, we have addressed the role of residue modification in catalytic activity and molecular recognition of an enzyme alpha ...
Pritam Biswas, Aniruddha Adhikari, Uttam Pal, Susmita Mondal, Dipanjan Mukherjee, Ria Ghosh, Rami J. Obaid, Ziad Moussa, Sudeshna Shyam Choudhury, Saleh A. Ahmed, Saleh A. Ahmed, Ranjan Das, Samir Kumar Pal, Samir Kumar Pal   +13 more
doaj   +1 more source

Enzymatic Pea Protein Hydrolysates Are Active Trypsin and Chymotrypsin Inhibitors

Foods, 2019
In this work, we report the potency of enzymatic hydrolysates of pea proteins against trypsin and chymotrypsin. Pea protein concentrate was digested with each of alcalase, chymotrypsin, pepsin, and trypsin, followed by membrane separation of the protein ...
Temitola Awosika, Rotimi E. Aluko
doaj   +1 more source

Influence of Green Synthesized Zinc Oxide Nanoparticles on Molecular Interaction and Comparative Binding of Azure Dye with Chymotrypsin: Novel Nano-Conjugate for Cancer Phototherapy

Pharmaceutics, 2022
Till date, different types of conventional drugs have been used to fight tumors. However, they have significant flaws, including their usage being constrained because of their low bioavailability, poor supply, and serious side effects.
Amit Singh, Pankaj Kumar, Niloy Sarkar, Mahima Kaushik   +3 more
doaj   +1 more source

Proximity-Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases. [PDF]

Angew Chem Int Ed Engl
A proximity‐induced, mass‐encoded activity‐based protein profiling (ABPP) approach transfers a MALDI‐detectable α‐cyano‐4‐hydroxycinnamic acid (CHCA) tag directly to active proteases. This tag enables the direct, multiplexed, and quantitative detection of enzyme activity in complex proteomes without enrichment or purification.
Berthy L, Pasco U, Sejalon-Cipolla M, Bruyat P, Kaminska M, Malgorn C, Beau F, Osolin M, Novak M, Breznik B, Georgiadis D, Correia I, Groult E, Lequin O, Bregant S, Pers YM, Noel D, Thai R, Subra G, Cantel S, Devel L.   +20 more
europepmc   +3 more sources

Oxygen‐Tolerant Photo‐Induced Miniaturized Accelerated Atom Transfer Radical Polymerization (OPTIMA‐ATRP) for High‐Throughput Synthesis of Polymer Bioconjugates

Angewandte Chemie, EarlyView.
Oxygen‐tolerant photo‐induced miniaturized accelerated atom transfer radical polymerization (OPTIMA‐ATRP) in water was developed for the polymerization of hydrophilic (meth)acrylate monomers under ambient or sub‐ambient (4°C) temperature and atmospheric conditions, without prior degassing, in less than 10 min, at an ultra‐small scale (< 50 µL) in ...
Arman Moini Jazani, Roksana Wygoda, Hironobu Murata, Mozhdeh Madadi, Grzegorz Przesławski, Krzysztof Matyjaszewski   +5 more
wiley   +2 more sources

Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]

, 2000
The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard, Valueva, Tatyana A., Revina, Tatyana A., Mosolov, Vladimir V.   +3 more
core   +1 more source

Dependence and Guidance Receptors—DCC and Neogenin—In Partial EMT and the Actions of Serine Proteases

Frontiers in Oncology, 2020
The Epithelial-Mesenchymal Transition (EMT) is an important concept in understanding the processes of oncogenesis, especially with respect to the relationship between cell proliferation and metastatic properties such as spontaneous cell motility ...
Trevor W. Stone
doaj   +1 more source

Zootechnical Parameters and Enzyme Activity in the Species Brycon moorei (Steindachner 1878)

Fishes, 2023
Brycon moorei is an opportunistic omnivorous species. It is not known what its nutritional requirements are at any stage of its development; this study determined the influence of diet on the zootechnical parameters and enzyme activity of these fish.
Carlos David-Ruales, Débora Machado Fracalossi, Felipe Collazos-Lasso   +2 more
doaj   +1 more source