Results 41 to 50 of about 3,488,373 (301)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Didáctica de las ciencias con conciencia
, 2018 En este articulo se hace un balance de los logros del pasado y los retos del futuro en el campo de la Didactica de las Ciencias. Se aporta una vision de los consensos mas importantes alcanzados por la comunidad investigadora y se sintetizan algunos ...
R. P. Ariza
semanticscholar +1 more source
South American dust signature in geological archives of the Southern Hemisphere [PDF]
, 2014 Patagonian dust is the darling of researchers of paleoclimatic variability of southern South America. However, new chemical data from yet unexplored dust source areas allows for deeper investigation of the geological archives in the region.Fil: Gili ...
Gaiero, Diego Marcelo, Gili, Stefania
core
Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA [PDF]
, 2012 The checkpoint kinases Chk1 and ATR are broadly known for their role in the response to the accumulation of damaged DNA. Because Chk1 activation requires its phosphorylation by ATR, it is expected that ATR or Chk1 down-regulation should cause similar ...
Federico, Maria Belén +4 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
TribunalLa deserción escolar es una de las principales problemáticas que presenta el sector educativo en Colombia, dicha problemática se genera por las diferentes situaciones sociales que vive el país y que ha vivido históricamente.
José Roberto Ochoa Gómez +2 more
doaj +1 more source
Didáctica de las ciencias experimentales en educación primaria
, 2017 A brief review of the book is presented : Rivero, A., Martin del Pozo, R., Solis, E. y Porlan, R. (2017). Didactica de las Ciencias Experimentales en Educacion Primaria. Madrid: Editorial Sintesis.
R. M. D. Pozo
semanticscholar +1 more source
Genes of different catabolic pathways are coordinately regulated by Dal81 in Saccharomyces cerevisiae [PDF]
, 2015 Yeast can use a wide variety of nitrogen compounds. However, the ability to synthesize enzymes and permeases for catabolism of poor nitrogen sources is limited in the presence of a rich one.
Bermudez Moretti, Mariana +2 more
core +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Telos: Revista de Estudios Interdisciplinarios en Ciencias SocialesEn la labor educativa, es importante reconocer el ingenio del docente para afrontar los desafíos en el quehacer pedagógico, buscando de esta manera innovar progresivamente la experiencia de enseñanza y aprendizaje.
Luis Orlando Chonillo-Sislema +3 more
doaj +1 more source