Results 161 to 170 of about 2,842 (212)
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Ciguatoxin: More Than an Anticholinesterase
Science, 1968Anticholinesterase action of ciguatoxin has been reported. A study of the pharmacology of the action of the toxin on the respiratory system suggests that additional properties may be involved in the respiratory failure—the usual cause of death in ciguatera poisoning.
M D, Rayner, T I, Kosaki, E L, Fellmeth
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Convergent and Scalable Synthesis of the ABCDE-Ring Fragment of Caribbean Ciguatoxin C-CTX-1.
Journal of Organic Chemistry, 2022Convergent and scalable synthesis of the ABCDE-ring fragment of Caribbean ciguatoxin C-CTX-1, the major causative toxin for ciguatera poisoning in the Caribbean Sea and the Northeast Atlantic areas, is described in detail.
M. Sasaki, Miku Seida, Atsushi Umehara
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Ciguatoxin: Isolation and Chemical Nature
Science, 1967Ciguatoxin, the agent responsible for ciguatera, a disease produced in humans from ingestion of certain fishes, has been isolated from specimens of the moray eel, Gymnothorax javanicus . The toxin is apparently a lipid containing quaternary nitrogen, hydroxyl, and carbonyl functions.
P J, Scheuer +3 more
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Polyneuropathy secondary to ciguatoxin poisoning
The Italian Journal of Neurological Sciences, 1988Following ingestion of marine fish in Thailand this patient complained of gastrointestinal and neurological disturbances, marked by severe, mainly motor, demyelinating polyneuropathy, which worsened on her return to Italy a few days later. The clinical pattern, electromyography, cerebrospinal fluid test and sural nerve biopsy by electronmicroscopy ...
Sozzi, G +4 more
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CABI Compendium, 2022
This datasheet on ciguatoxin poisoning covers Identity.
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This datasheet on ciguatoxin poisoning covers Identity.
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Total Synthesis of Ciguatoxin CTX3C
Science, 2001More than 20,000 people suffer annually from ciguatera seafood poisoning in subtropical and tropical regions. The extremely low content of the causative neurotoxins, designated as ciguatoxins, in fish has hampered the isolation, detailed biological studies, and preparation of anti-ciguatoxin antibodies for detecting these toxins.
M, Hirama +6 more
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Two interchangeable forms of ciguatoxin
Toxicon, 1984Ciguatoxin, the principal toxin responsible for ciguatera, isolated from moray eel viscera, has been separated into two distinct components by alumina chromatography. A series of chromatographies showed that the two components are interchangeable. This proves that ciguatoxin is a single molecular entity.
M, Nukina, L M, Koyanagi, P J, Scheuer
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Chemistry Letters
Ciguatera poisoning (CP) is a recognized foodborne illness resulting from consuming fish with accumulated low levels of ciguatoxins (CTXs). Each year, over 50,000 people are affected by CP.
T. Tsumuraya, Masahiro Hirama
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Ciguatera poisoning (CP) is a recognized foodborne illness resulting from consuming fish with accumulated low levels of ciguatoxins (CTXs). Each year, over 50,000 people are affected by CP.
T. Tsumuraya, Masahiro Hirama
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Ciguatoxin reduces larval survivability in finfish
Toxicon, 1999Ciguatoxins are lipophilic polyether toxins which concentrate in the viscera and flesh of coral reef associated finfish (Hessel et al., 1960). In this study, we quantify the adverse effects of ciguatoxin on fish embryos by microinjection into the egg yolk of medaka (Oryzias latipis) embryos. Embryos microinjected with 0.1-0.9 pg/egg (ppb) of ciguatoxin
J S, Edmunds +2 more
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Ciguatoxins are potent ichthyotoxins
Toxicon, 1992The ciguatoxins are lipid soluble polyether compounds which have structural and biochemical features in common with the brevetoxins. Pure ciguatoxin-1, ciguatoxin-2 or brevetoxin-2 added to water containing Gambusia affinis induced similar signs, including pronounced opercular movement and uncoordinated swimming preceding death. The estimated LD50s (48
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