A General Food Chain Model for Bioaccumulation of Ciguatoxin into Herbivorous Fish in the Pacific Ocean Suggests Few <i>Gambierdiscus</i> Species Can Produce Poisonous Herbivores, and Even Fewer Can Produce Poisonous Higher Trophic Level Fish. [PDF]
Holmes MJ, Lewis RJ.
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An Unusual Presentation of Severe Ciguatera Poisoning: Case Report. [PDF]
Bengio M +3 more
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Targeted Metabolite Fingerprints of Thirteen Gambierdiscus, Five Coolia and Two Fukuyoa Species. [PDF]
Murray JS +12 more
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Faster ciguatoxin extraction methods for toxicity screening. [PDF]
Loeffler CR, Spielmeyer A.
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Gambierdiscus species diversity and community structure in St. Thomas, USVI and the Florida Keys, USA. [PDF]
Richlen ML +7 more
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Transcriptomic insights into polyketides and toxin biosynthesis genes in freshwater dinoflagellates. [PDF]
Muhammad BL, Bui QTN, Kim HS, Ki JS.
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Ciguatoxin-2 is a diastereomer of ciguatoxin-3
Toxicon, 1993Ciguatoxin-2, a major ciguatoxin present in the flesh and viscera of ciguateric fishes, has been shown by 1H nuclear magnetic resonance studies (2-dimensional homonuclear Hartman Hahn, nuclear Overhauser effect and decoupling difference experiments) to be a diastereomer of ciguatoxin-3, differing only in stereochemistry at carbon 52 (a quaternary ...
Lewis, RJ +3 more
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AbstractEines der Haupttoxine bei Fischvergiftungen, das Ciguatoxin (siehe Struktur), war Ziel einer Totalsynthese. Der Syntheseweg beruht auf der Kupplung dreier Segmente, und die Schlüsselumwandlungen umfassen eine Komplexbildung zwischen Acetylen und Dicobalthexacarbonyl.magnified ...
Akinari, Hamajima, Minoru, Isobe
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Ciguatoxin: More Than an Anticholinesterase
Science, 1968Anticholinesterase action of ciguatoxin has been reported. A study of the pharmacology of the action of the toxin on the respiratory system suggests that additional properties may be involved in the respiratory failure—the usual cause of death in ciguatera poisoning.
M D, Rayner, T I, Kosaki, E L, Fellmeth
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Ciguatoxin: Isolation and Chemical Nature
Science, 1967Ciguatoxin, the agent responsible for ciguatera, a disease produced in humans from ingestion of certain fishes, has been isolated from specimens of the moray eel, Gymnothorax javanicus . The toxin is apparently a lipid containing quaternary nitrogen, hydroxyl, and carbonyl functions.
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