Results 91 to 100 of about 56,100 (193)

Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Gastrointestinal Tumors

Journal of Immunology Research, 2014
Tumors of the gastrointestinal system represent a significant share of solid tumors worldwide. Despite the advances in diagnosis and treatment, the prognosis of gastrointestinal tumors is still very poor and improved therapies are indispensable. Cytokine-
Clara E. Jäkel, Annabelle Vogt, Maria A. Gonzalez-Carmona, Ingo G. H. Schmidt-Wolf   +3 more
doaj   +1 more source

Retrospective analysis of the efficacy of cytokine‐induced killer cell immunotherapy combined with first‐line chemotherapy in patients with metastatic colorectal cancer

Clinical & Translational Immunology, 2020
Objectives Fluoropyrimidine‐based chemotherapy regimens are the current first‐line treatment for metastatic colorectal cancer (mCRC); however, the outcome is often unsatisfactory.
Qiu‐Zhong Pan, Jia‐Mei Gu, Jing‐Jing Zhao, Yan Tang, Qi‐Jing Wang, Qian Zhu, Meng‐Jia Song, Yong‐Qiang Li, Jia He, Shi‐Ping Chen, De‐Sheng Weng, Jian‐Chuan Xia   +11 more
doaj   +1 more source

树突状细胞对细胞因子诱导的杀伤细胞增殖和抗白血病作用影响的研究

Zhongguo shiyan zhenduanxue, 2007
目的探讨树突状细胞（DC）对细胞因子诱导的杀伤细胞（CIK）增殖能力、免疫表型、分泌细胞因子水平以及抗白血病细胞作用的影响。方法健康人外周血单个核细胞诱导DC和CIK细胞,将DC与CIK共培养,以CIK细胞单独培养为对照。用台盼蓝活细胞计数计算细胞扩增倍数,MTT法测定杀伤活性,流式细胞术分析免疫表型,ELISA双抗体夹心法检测分泌干扰素-γ（IFN-γ）、白细胞介素-12（IL-12）的水平。结果DC-CIK细胞增殖能力明显高于CIK细胞 ...
魏绪仓, 赵文理, 连小云, 杨娣娣, 韩秀蕊, 邢佩霓, 李梅生   +6 more
doaj  

Discovering single cannabidiol or synergistic antitumor effects of cannabidiol and cytokine-induced killer cells on non-small cell lung cancer cells

Frontiers in Immunology
IntroductionA multitude of findings from cell cultures and animal studies are available to support the anti-cancer properties of cannabidiol (CBD). Since CBD acts on multiple molecular targets, its clinical adaptation, especially in combination with ...
Yutao Li, Amit Sharma, Amit Sharma, Michèle J. Hoffmann, Dirk Skowasch, Markus Essler, Hans Weiher, Ingo G. H. Schmidt-Wolf   +7 more
doaj   +1 more source

Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Renal Cell Carcinoma

Clinical and Developmental Immunology, 2012
Metastatic renal cell carcinoma (RCC) seems to be resistant to conventional chemo- and radiotherapy and the general treatment regimen of cytokine therapy produces only modest responses while inducing severe side effects.
Clara E. Jäkel, Stefan Hauser, Sebastian Rogenhofer, Stefan C. Müller, P. Brossart, Ingo G. H. Schmidt-Wolf   +5 more
doaj   +1 more source

Cell-based immunotherapy with cytokine-induced killer (CIK) cells: From preparation and testing to clinical application

Human Vaccines & Immunotherapeutics, 2017
Cell-based immunotherapy holds promise in the quest for the treatment of cancer, having potential synergy with surgery, chemotherapy and radiotherapy.
Yiming Meng, Zhifu Yu, Yefeng Wu, Tianzhao Du, Shi Chen, Fanjuan Meng, Nan Su, Yushu Ma, Xiaoxi Li, Sulan Sun, Guirong Zhang   +10 more
doaj   +1 more source

Cytokine-induced killer cells: new insights for therapy of hematologic malignancies

Stem Cell Research & Therapy
Background Cytokine-induced killer (CIK) cells are a novel subgroup of immune effectors, classified as one of the modified T cell-mediated arms for immunotherapy.
Faezeh Ghanbari Sevari, Amir Mehdizadeh, Khadijeh Abbasi, Seyyed Sina Hejazian, Mortaza Raeisi   +4 more
doaj   +1 more source

Strategi Cik Uniang Cik Ajo Duta Wisata Dalam Rangka Transformasi Promosi Pariwisata di Kota Pariaman

Jurnal ISO: Jurnal Ilmu Sosial, Politik dan Humaniora
Tujuan dari penelitian ini adalah untuk mengkaji pelaksanaan transformasi promosi pariwisata di kota Pariaman yang dilakukan oleh Cik Uniang Cik Ajo duta wisata dengan menganalisis strategi serta menetapkan strategi yang tepat. Latar belakang penelitian ini adalah belum optimalnya kegiatan promosi pariwisata yang dilakukan oleh Cik Uniang Cik Ajo duta ...
Lidiya Wahyuni, Aldri Frinaldi
openaire   +1 more source

Synergistic integration of histone deacetylase inhibitors apparently enhances the cytokine‐induced killer cell efficiency in multiple myeloma via the NKG2D pathway

Clinical & Translational Immunology
Objectives The rapid recognition of epigenetic manipulation's potential in restricting cancer cell capabilities spurred translational initiatives, including histone deacetylase inhibitors (HDACis).
Jingjing Pu, Amit Sharma, Ting Liu, Jian Hou, Ingo GH Schmidt‐Wolf   +4 more
doaj   +1 more source

[Researche advances on CIK cells and their clinical use in lung cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2011
As the leading cause of cancer-related death among human beings, lung cancer seriously threats peoples' health all over the world. Cytokine-induced killer cells (CIK) is a new kind of adaptive immune cells characterized by its dramatic proliferation ability and cytotoxicity, non-major histocompatibility antigens (MHC) restriction and low side effects ...
Hu LUO, Xiangdong ZHOU
openaire   +2 more sources