Results 71 to 80 of about 3,955 (172)
Plant Biotechnology Journal, EarlyView.ABSTRACT Steviol glycosides (SGs) are a group of sweet‐tasting diterpene glycosides found in Stevia rebaudiana. Production of high‐value SGs, Rebaudioside D (Reb D) and Reb M, is limited by inefficient conversion of Reb A to Reb D and stevioside to Reb E.
Sing Hui Leong +3 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 5, September 2026.Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
Clinical and Developmental Immunology, 2012 Adoptive therapy of malignant diseases with cytokine-induced killer (CIK) cells showed promise in a number of trials; the activation of CIK cells from cancer patients towards their autologous cancer cells still needs to be improved.
Claudia Schlimper +3 more
doaj +1 more source
Cytokine Induced Killer (CIK) Cells Based Adoptive Immunotherapy
Journal of Gandaki Medical College, 2018 Cytokine induced killer (CIK) cells has been increasingly used in adoptive immunotherapy against various cancers and viral infections. This review summarizes the basic overview of CIK cells as a therapeutic immunocyte.
S Timalsena, P P Lamichhane
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Pharmaceuticals, 2020 Cytokine-induced killer (CIK) cells are advanced therapy medicinal products, so their production and freezing process has to be validated before their clinical use, to verify their stability as a drug formulation according to the good manufacturing ...
Katia Mareschi +10 more
doaj +1 more source
Cancer, Volume 132, Issue 16, 15 August 2026.Abstract Background Disease‐free survival (DFS) is commonly used as a primary end point in trials for localized renal cell carcinoma (RCC), although its validity as a surrogate for overall survival (OS) remains uncertain. The objective of this study was to evaluate whether DFS is a reliable surrogate end point for OS in this setting.
Constanza Martinez +7 more
wiley +1 more source
Journal of Immunology Research, 2018 Objective. DC-CIK therapy included DC-CIK cells and Ag-DC-CIK cells. To further confirm whether DC-CIK reconstructs the antitumor immunity and improves the tumor responses and reveals its optimal usage and combination with chemotherapy, we systematically
Zheng Xiao +12 more
doaj +1 more source
Clinical Trial Analysis of Different Stages of HBV Patients Treated with Human CIK Cells
Nano Biomedicine and Engineering, 2016 Cellular immunotherapy has become a potential therapeutic method for different diseases. Herein, we reported clinical trial results of Cytokine-induced killer (CIK) cells used for patients with hepatitis B, cirrhosis and liver cancers from 2000 to 2015 ...
Fangfang Xia +13 more
doaj +1 more source
Observation of Excitonic Instability in a Monolayer Ta2NiSe5 With Strain Disorder
Advanced Science, Volume 13, Issue 43, 3 August 2026.Monolayer Ta2${\rm Ta}_2$NiSe5${\rm NiSe}_5$ sustains an excitonic insulating phase up to 190 K, with Raman signatures of gap opening and critical excitonic fluctuations. Thickness‐independent large gap ratios highlight strong exciton‐phonon coupling, while substrate‐induced strain disorder depresses Tc, establishing monolayer Ta2${\rm Ta}_2$NiSe5${\rm
So Young Kim +13 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Acute myeloid leukemia (AML) is a disease characterized by uncontrolled proliferation and blocked maturation of hematopoietic stem and progenitor cells. Despite progress in its clinical management, many patients continue to relapse or show limited response to standard therapies, emphasizing the need for novel, safe, and more effective targeted ...
Rongrong Hu, Zaker Ataullev, Luping Lou
wiley +1 more source