Results 81 to 90 of about 3,955 (172)
Zhongguo shiyan zhenduanxue, 2015 目的探讨DC(dendritic cells)、CIK(cytokine-induced killer cells)联合培养对肺腺癌细胞A549的杀伤活性的影响,并与单独CIK对A549杀伤活性进行比较,为肿瘤生物治疗提供有效方法。方法分别培养DC、CIK细胞,经鉴定后进行联合培养,联合培养3天后,对A549细胞进行杀伤活性实验,检测DC联合CIK及单独CIK对A549的杀伤活性,同时用流式细胞检测DC、CIK联合培养细胞及单独CIK细胞中淋巴细胞亚群的表达。结果 ...
赵鑫 +8 more
doaj
Frontiers in Pharmacology, 2018 Cytokine-induced killer (CIK) cells, a heterogeneous T cell population obtained by in vitro differentiation of peripheral blood mononuclear cells (PBMC), represent a promising immunological approach in cancer.
Alberto L. Horenstein +8 more
doaj +1 more source
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 8, August 2026.The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source
THERMAL COMFORT SIMULATION ON CIK DITIRO CORRIDOR
DIMENSI (Journal of Architecture and Built Environment), 2019 Surface materials that turn into hard surface material and lack of vegetations are some of the effects of rapid development that can affect the micro climate in urban areas. This happened on Cik Ditiro corridor in the city of Yogyakarta which had quite dense activities, this was marked by various functions of land use and human activities throughout ...
Septian Eka Prayoga, Arif Kusumawanto
openaire +3 more sources
Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment
Immunology &Cell Biology, Volume 104, Issue 7, Page 711-728, August 2026.Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari +6 more
wiley +1 more source
Analytic and Dynamic Secretory Profile of Patient-Derived Cytokine-lnduced Killer Cells
Molecular Medicine, 2017 Adoptive immunotherapy with cytokine induced killer (CIK) cells has shown antitumor activity against several kinds of cancer in preclinical models and clinical trials.
Giulia Mesiano +13 more
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Frontiers in ImmunologyIntroductionA multitude of findings from cell cultures and animal studies are available to support the anti-cancer properties of cannabidiol (CBD). Since CBD acts on multiple molecular targets, its clinical adaptation, especially in combination with ...
Yutao Li +7 more
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Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Gastrointestinal Tumors
Journal of Immunology Research, 2014 Tumors of the gastrointestinal system represent a significant share of solid tumors worldwide. Despite the advances in diagnosis and treatment, the prognosis of gastrointestinal tumors is still very poor and improved therapies are indispensable. Cytokine-
Clara E. Jäkel +3 more
doaj +1 more source
树突状细胞对细胞因子诱导的杀伤细胞增殖和抗白血病作用影响的研究
Zhongguo shiyan zhenduanxue, 2007 目的探讨树突状细胞（DC）对细胞因子诱导的杀伤细胞（CIK）增殖能力、免疫表型、分泌细胞因子水平以及抗白血病细胞作用的影响。方法健康人外周血单个核细胞诱导DC和CIK细胞,将DC与CIK共培养,以CIK细胞单独培养为对照。用台盼蓝活细胞计数计算细胞扩增倍数,MTT法测定杀伤活性,流式细胞术分析免疫表型,ELISA双抗体夹心法检测分泌干扰素-γ（IFN-γ）、白细胞介素-12（IL-12）的水平。结果DC-CIK细胞增殖能力明显高于CIK细胞 ...
魏绪仓 +6 more
doaj
Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Renal Cell Carcinoma
Clinical and Developmental Immunology, 2012 Metastatic renal cell carcinoma (RCC) seems to be resistant to conventional chemo- and radiotherapy and the general treatment regimen of cytokine therapy produces only modest responses while inducing severe side effects.
Clara E. Jäkel +5 more
doaj +1 more source