Results 181 to 190 of about 80,298 (298)

Liver disease reveals KIF12 as a regulator of mitochondria, lysosome and cilia localisation in human cholangiocytes. [PDF]

EBioMedicine
Seth A, Brancale J, Dashti-Gibson N, Florentino RM, Faccioli LAP, Liu Z, Konkwo C, Hong H, Soto-Gutierrez A, Vilarinho S.   +9 more
europepmc   +1 more source

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

Phytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng, Xuelian Yuan, Yawen Xie, Zhenni Xia, Zhaohui Guo, Xuesong Liu, Rong Li, Wenliang Wang   +7 more
wiley   +1 more source

Selective loss of primary cilia and neurotrophic signaling in G51D α-synuclein mice highlights a common pathway to Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Lin YE, Jaimon E, Kim Y, Loftman A, Vijayakumaran A, Belfort BDW, Chiang CY, Arenkiel BR, Zoghbi HY, Pfeffer SR.   +9 more
europepmc   +1 more source

Primary cilia

Journal of Oral and Maxillofacial Pathology, 2017
openaire   +3 more sources

Intelligent Continuum Micromachines in Complex Confined Spaces

SmartBot, EarlyView.
The cover depicts a conceptual design for an intelligent continuum micromachine entering a target capsule used in fusion‐energy research through its slender gas‐fill tube. By combining route‐adaptive deformation, embedded sensing, and a functional end effector, the robot could inspect hidden defects, assess local conditions, and support localized ...
Huayang Sai, Yunyue Yang, Shuxing Xu, Jinbo Hu, Jiliang Wang, Zhehao Gan, Wei Tang, Tian‐Yun Huang   +7 more
wiley   +1 more source

The primary cilium-autophagy axis in vascular homeostasis and cardiovascular disease: mechanistic crosstalk and evidence boundaries. [PDF]

Front Cardiovasc Med
Fu X, Zhou W, Zhang C, Bai Y.
europepmc   +1 more source

Multi‐Scale Magnetically Controlled Soft Matter Robots for Tissue Interfacing Applications

SmartBot, EarlyView.
Magnetically controlled soft matter robots (MSMRs) integrate remote magnetic control with soft matter adaptability for minimally invasive biomedical tasks at tissue interfaces across multiple scales. This review examines the interaction mechanisms between MSMRs and tissue interfaces, with MSMRs classified into five categories according to their ...
Wenxin Lian, Yan Zhou, Dianhong Zhang, Yuanwen Liang, Zihao Tang, Zhuo Chen, Qichen Hong, Jiangfan Yu, Chi Zhang, Xiaopu Wang   +9 more
wiley   +1 more source

Primary cilia connect epithelial mesenchymal plasticity with anoikis resistance and cancer stemness. [PDF]

Discov Oncol
Chen Q, Yang J, Yu J, Jiang S, Zhang J.
europepmc   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source

tArp Is an Actin-Related Protein Required for Ciliary Function That Is Conserved in Ciliates and Related Eukaryotic Groups. [PDF]

J Eukaryot Microbiol
Kagawa M, Hagita M, Nakayama T, Shiba K, Kato-Minoura T, Matsuda S, Inaba K, Inagaki Y, Nakano K.   +8 more
europepmc   +1 more source