Results 191 to 200 of about 80,298 (298)

Detection and Inhalation Hazard Assessment of Wear Particles Arising From Abrasion of Market‐relevant Graphene Reinforced Composites

Small, EarlyView.
Abrasion of few‐layer graphene (FLG)–epoxy composites generated respirable particles in which FLG remained fully embedded, as confirmed by correlative HR‑TEM, Raman, and ToF‑SIMS analyses. Advanced lung cell models revealed no cytotoxic or inflammatory responses, and only high‑dose epoxy particles reduced mucociliary clearance.
Govind Gupta, Jimmy Vernaz, Antje Vennemann, Maike Stange, Asmus Meyer‐Plath, Servane Contal, Sarah Zehnder, Ziting Wang, Aline Chary, Stephanie Eitner, Philipp Mueller, Vera M. Kissling, Samuel Constant, Lucie Chupin, Daniel Breitenstein, Birgit Hagenhoff, Tommaso Serchi, Bernadett Boda, Martin Wiemann, Peter Wick, Tina Buerki‐Thurnherr   +20 more
wiley   +1 more source

Dynamic regulation of hypothalamic NPY2R-positive primary cilia by nutritional states. [PDF]

Front Cell Dev Biol
Hamamoto A, Nishimura N, Saito Y, Kobayashi Y.   +3 more
europepmc   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

Small Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo, Egor Kokin, Sangyul Baik, Chanyong Park, Minji Kim, Jeongmin Kim, Ryungeun Song, Hosub Lim   +7 more
wiley   +1 more source

Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis. [PDF]

Brain
Bigotte M, Groh AMR, Afanasiev E, Wong V, Lancon K, Yaqubi M, Creeggan F, Sinott A, Pei J, Moore CS, Harroud A, Schneider R, Séguéla P, Charabati M, Tea F, Fournier AP, Wang YC, Ragoussis J, Prat A, Thebault S, Zandee S, Stratton JA.   +21 more
europepmc   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

Environmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff, Jessica Reinert, Silke Steinborn, Marion Berger, Judith Neuhoff, Lennart Marske, Kerttu Valtanen, Udo Jäckel, Stefanie Klar   +8 more
wiley   +1 more source

DNAAF19-RUVBL1/2 complex recruits multiple adaptors to promote dynein arm assembly. [PDF]

Proc Natl Acad Sci U S A
de Almeida Gomes M, Wood E, Burgoyne T, Klose F, Batrinu D, Boldt K, Carrington G, Halfon Y, George R, Khan GN, Beyer T, Mitchison HM, Ochi T.   +12 more
europepmc   +1 more source

Oral non‐steroidal anti‐inflammatory drugs do not delay corneal healing in dogs with spontaneous chronic corneal epithelial defects: A retrospective cohort of 186 ulcers

Veterinary Record, EarlyView.
Abstract Background Oral non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for analgesia in dogs with spontaneous chronic corneal epithelial defects (SCCEDs). Topical NSAIDs can delay epithelialisation and promote stromal melting, but the safety of systemic NSAIDs in SCCEDs is unknown.
Kaitlyn Scheunemann, Rachel Allbaugh, Lionel Sebbag   +2 more
wiley   +1 more source

Cells and Organelles - Cilia

Many cells of the tracheal epithelium have hairlike structures at their apical borders called cilia. These cilia contain ordered arrays of microtubules, one of the three components of the cytoskeleton. Movements of the cilia transport mucus and dust from
Gorski, Roger A.
core  

In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia. [PDF]

Science
Zhou H, Terbeck L, Berical A, Brunet M, Lange SM, Anderson JR, Olbrich H, Bracht DC, Wohlgemuth K, Rieck C, Raidt J, Klingauf J, Sutharsan S, Mussaffi H, Prais D, Dunphy V, Homma ST, Guichard P, Hamel V, Hawkins FJ, Omran H, Brown A.   +21 more
europepmc   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source