Centrosomal JAK2 Tyrosine Kinase Regulates Primary Cilia Length, Cell Proliferation, and Cilia Orientation During Cell Migration. [PDF]
Karki G +7 more
europepmc +1 more source
Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang +4 more
wiley +1 more source
The development of a methodology to measure primary ciliary length in neural progenitor cells with a target molecule knocked down. [PDF]
Saito M, Otsu W, Ishibashi K, Atsumi GI.
europepmc +1 more source
ABSTRACT Background Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research on each factor individually, their combined pathological effects remain poorly understood.
Yunlong Yao +12 more
wiley +1 more source
Catalytic activity of KMT5B promotes ciliogenesis without affecting global chromatin accessibility. [PDF]
Tait J +5 more
europepmc +1 more source
Development of a Swine Whole Eye Transplant Ex Vivo Perfusion Protocol
This study establishes the first subnormothermic machine perfusion protocol for whole eye transplants in a swine model, enabling up to 18 h of preservation with stable metabolic function, limited edema, and recovery of mydriasis. ABSTRACT Background The first human Whole Eye Transplant (WET) has sparked new hope for patients who have lost vision due to
Haïzam Oubari +8 more
wiley +1 more source
Patient-informed CRISPR screen identifies FLNB as a congenital heart disease and ciliopathy gene. [PDF]
Arrigo A, Rao V, Ratan A, Kulkarni SS.
europepmc +1 more source
Abstract Purpose To analyse pain sensation after phototherapeutic keratectomy (PTK) using chilled eye drops or drops at room temperature during the early postoperative period. Methods Our randomised controlled, parallel‐group study conducted in the Department of Ophthalmology, Goethe‐University, Frankfurt (Main), Germany, with blinded participants and ...
Carolin Marion Kolb‐Wetterau +7 more
wiley +1 more source
MI-181 enhances ciliation and cilia length in a cigarette smoke exposed airway epithelial model. [PDF]
Gholkar AA +6 more
europepmc +1 more source
The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg +9 more
wiley +1 more source

