Results 211 to 220 of about 71,498 (314)

Identification of drug repurposing candidates for the treatment of polycystic kidney disease

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer   +9 more
wiley   +1 more source

Melanocortin 3 Receptors Do Not Specifically Localize to Primary Cilia in Cultured Human and Rodent Neurons. [PDF]

open access: yesCell Biochem Funct
Vos N   +8 more
europepmc   +1 more source

Primary cilia

open access: yesJournal of Oral and Maxillofacial Pathology, 2017
openaire   +3 more sources

Establishing a Zebrafish Functional Assay to Assess the Pathogenicity of Variants of Uncertain Significance in Ciliopathies. [PDF]

open access: yesEur J Clin Invest
Aresi C   +8 more
europepmc   +1 more source

Phenotypic Expansion and Molecular Implications in Recessive FUZ‐Related Ciliopathy

open access: yesClinical Genetics, EarlyView.
Our patient with homozygous FUZ p.Arg234Trp, potentially altering FUZ‐CPLANE2 interactions, presented with aorto‐pulmonary window, Hirschsprung disease, and shared phenotypes with previously reported ciliopathy patients. This report provides additional evidence for FUZ as a causative gene for ciliopathy, offering novel insights into the phenotype ...
Yosuke Ogawa   +4 more
wiley   +1 more source

Primary cilia in the hypothalamic AgRP neurons mediate metabolic effects of butyrate. [PDF]

open access: yesNat Commun
Rijal S   +7 more
europepmc   +1 more source

A new pest recorded in Italy: The South African citrus thrips, Scirtothrips aurantii (Thysanoptera: Thripidae)

open access: yesEPPO Bulletin, EarlyView.
Abstract The South African citrus thrips, Scirtothrips aurantii Faure, 1929, has been recorded in Italy for the first time. This species was recently reported in Spain and Portugal. Its presence has been confirmed in the major citrus‐growing area of Catania province (Sicily), infesting citrus trees. S. aurantii is currently included in the EPPO A1 List
Giuseppe Massimino Cocuzza   +3 more
wiley   +1 more source

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