Results 191 to 200 of about 53,416 (270)

Correction: A New TGF-β Mimetic, XEP™-716 Miniprotein™, Exhibiting Regenerative Properties Objectivized by Instrumental Evaluation

open access: yesDermatology and Therapy
Hanane Chajra   +6 more
doaj   +1 more source

KIF9 Ameliorates Neuropathology and Cognitive Dysfunction by Promoting Macroautophagy in a Mouse Model of Alzheimer's Disease

open access: yesAging Cell, EarlyView.
KIF9 is downregulated in AD, accompanied by dysfunction in macroautophagy. Genetic upregulation of KIF9 enhances macroautophagy by promoting KLC1‐mediated anterograde transport of lysosomes, which effectively reduces Aβ deposition and alleviates cognitive impairments in AD.
Maoju Wang   +10 more
wiley   +1 more source

A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification. [PDF]

open access: yesNat Commun
Wiegering A   +12 more
europepmc   +1 more source

Transcriptional Heterogeneity and Differential Response of Rod Photoreceptor Pathway Uncovered by Single‐Cell RNA Sequencing of the Aging Mouse Retina

open access: yesAging Cell, EarlyView.
Healthy aging is accompanied by transcriptional dysregulation in retinal cells, leading to alterations in key molecular pathways and cellular responses, with the scotopic pathway being particularly affected. We show that rod photoreceptors, essential for initiating scotopic (low‐light) vision, exhibit selective vulnerability to aging‐associated ...
Laura Campello   +5 more
wiley   +1 more source

Core N-DRC components play a crucial role in embryonic development and postnatal organ development. [PDF]

open access: yesCell Death Dis
Ren C   +8 more
europepmc   +1 more source

Aging‐Associated Vacuolation of Multi‐Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment

open access: yesAging Cell, EarlyView.
Multi‐ciliated cells in the infundibulum and ampulla (INF/AMP) epithelium are vacuolated in aging. Unique cellular susceptibility of the INF/AMP epithelial population and aging‐associated decline in ovarian artery circulation, which supports the ovary and INF/AMP, contribute to this region‐specific vacuolation phenotype, as a consequence of a mildly ...
Keerthana Harwalkar   +10 more
wiley   +1 more source

The impacts of e‐cigarette flavours: An overview of systematic reviews

open access: yesAddiction, EarlyView.
Abstract Background and Aims E‐cigarette flavours have the potential to impact the appeal, harms and use of e‐cigarettes and combustible tobacco. Systematic reviews have synthesised evidence on their impacts but have always focused on specific outcomes or populations.
Jonathan Livingstone‐Banks   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy