Results 201 to 210 of about 9,541 (228)
Functional interaction between autophagy and ciliogenesis [PDF]
Nature, 2013 Nutrient deprivation is a stimulus shared by both autophagy and the formation of primary cilia. The recently discovered role of primary cilia in nutrient sensing and signalling motivated us to explore the possible functional interactions between this signalling hub and autophagy.
Olatz Pampliega, I Orhon, Isabelle Beau
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Nature Cell Biology, 2014
ABCC4 is a member of the ATP-binding cassette transporter family known to transport prostaglandin E2 and other molecules across cellular membranes. A mutation in ABCC4 is now shown to cause defects in ciliogenesis, revealing a role for prostaglandin signalling in regulating cilia dynamics.
Pascal Barbry, Laure-Emmanuelle Zaragosi
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ABCC4 is a member of the ATP-binding cassette transporter family known to transport prostaglandin E2 and other molecules across cellular membranes. A mutation in ABCC4 is now shown to cause defects in ciliogenesis, revealing a role for prostaglandin signalling in regulating cilia dynamics.
Pascal Barbry, Laure-Emmanuelle Zaragosi
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Prostaglandin signaling in ciliogenesis and development
Journal of Cellular Physiology, 2021AbstractProstaglandin (PG) signaling regulates a wide variety of physiological and pathological processes, including body temperature, cardiovascular homeostasis, reproduction, and inflammation. Recent studies have revealed that PGs play pivotal roles in embryo development, ciliogenesis, and organ formation. Prostaglandin E2 (PGE2) and its receptor EP4
Daqing Jin, Tao P. Zhong
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Ciliogenesis and ciliary abnormalities
Medical Electron Microscopy, 2000Cilia are motile processes extending from the basal bodies, playing important roles in the mucociliary clearance in the respiratory tract and the transport of the ovum from the ovary to the uterus in mammals. Ciliogenesis is divided into four stages: (1) duplication of centrioles; (2) migration of centrioles to the apical cell surface to become basal ...
Nobuo Ohwada +3 more
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Roles of the actin cytoskeleton in ciliogenesis
Journal of Cell Science, 2022ABSTRACT Primary cilia play a key role in the ability of cells to respond to extracellular stimuli, such as signaling molecules and environmental cues. These sensory organelles are crucial to the development of many organ systems, and defects in primary ciliogenesis lead to multisystemic genetic disorders, known as ciliopathies. Here, we
Huxley K. Hoffman, Rytis Prekeris
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Ciliogenesis of The Retinal Photoreceptor
Proceedings, annual meeting, Electron Microscopy Society of America, 1980Development of the modified cilium in rod photoreceptors is unique in that, unlike other ciliated epithelia, the photoreceptor cilium does not project into a free lumen but rather abuts against the apex of another epithelial cell, i.e. pigmented epithelium.
Jack V. Greinert +2 more
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Protocols to induce and study ciliogenesis
2023Primary cilia (PC) are sensory organelles that function as cellular antennas, transmitting signals between the extracellular and intracellular spaces in many vertebrate tissues. The cell generates and assembles PC through a highly regulated process called ciliogenesis.
Paula, Moreno-Cruz +4 more
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Ciliogenesis in photoreceptor cells of the retina
Experimental Eye Research, 1981Ciliogenesis in the retinal photoreceptor of fetal, neonatal and adult ferrets has been investigated by electron microscopy. Ciliogenesis is described from the time (prenatal day 21) when a diplosome (two centrioles) is observed migrating toward the region of the external limiting membrane prior to eventual alignment beneath the apical plasma membrane ...
H. Daniel Bodley +5 more
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Development of order during ciliogenesis
The Anatomical Record, 1968AbstractThis report consists of an electron microscope study of developing cilia in nasal epithelium of 15–18 day mouse embryos. As soon as recognizable cilia were observed, the typical 9 + 2 pattern of ciliary microtubule pairs was present. However, at this stage the intracellular spatial alignment of adjacent cilia, reflected in the adult by ...
Donald Frisch, Albert I. Farbman
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Motile ciliogenesis and the mitotic prism
Biology of the Cell, 2019AbstractMotile cilia of epithelial multiciliated cells transport vital fluids along organ lumens to promote essential respiratory, reproductive and brain functions. Progenitors of multiciliated cells undergo massive and coordinated organelle remodelling during their differentiation for subsequent motile ciliogenesis.
Nathalie Spassky +6 more
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