Results 271 to 280 of about 21,394 (289)

Emerging insights into CP110 removal during early steps of ciliogenesis.

Journal of Cell Science
The primary cilium is an antenna-like projection from the plasma membrane that serves as a sensor of the extracellular environment and a crucial signaling hub.
Shuwei Xie, Naava Naslavsky, Steve Caplan   +2 more
semanticscholar   +1 more source

Probing Ciliogenesis Using Micropatterned Substrates

2013
The primary cilium is a biomechanical sensor plugged in at the cell surface. It is implicated in the processing of extracellular signals and its absence or misfunctioning lead to a broad variety of serious defects known as ciliopathies. Unfortunately, the precise mechanisms underlying primary cilium assembly and operation are still poorly understood ...
Pitaval, Amandine, Christ, Andreas, Curtet, Alexis, Tseng, Qingzong, Théry, Manuel   +4 more
openaire   +5 more sources

TMEM216 promotes primary ciliogenesis and Hedgehog signaling through the SUFU-GLI2/GLI3 axis

Science Signaling
Primary cilia are enriched in signaling receptors, and defects in their formation or function can induce conditions such as polycystic kidney disease, postaxial hexadactyly, and microphthalmia.
Yingying Wang, Huili Yao, Yu Zhang, Ning Mu, Tong Lu, Zhiyuan Du, Yingdi Wu, Xiaopeng Li, Min Su, Ming Shao, Xiaoyang Sun, Ling Su, Xiangguo Liu   +12 more
semanticscholar   +1 more source

Motile ciliogenesis and the mitotic prism

Biology of the Cell, 2019
AbstractMotile cilia of epithelial multiciliated cells transport vital fluids along organ lumens to promote essential respiratory, reproductive and brain functions. Progenitors of multiciliated cells undergo massive and coordinated organelle remodelling during their differentiation for subsequent motile ciliogenesis.
Adel Al Jord, Nathalie Spassky, Alice Meunier   +2 more
openaire   +2 more sources

Ciliogenesis in Cultured Human Nasal Epithelium

ORL, 1990
Human nasal epithelial cells, which lost their cilia in monolayer cultures, redeveloped cilia after 1 week in a suspension culture system. Before ciliogenesis started, the number of microvilli increased. Primary cilia were absent. The different cytoplasmic stages of this in vitro ciliogenesis could be reconstructed here into a sequence of events ...
M, Jorissen, B, Van der Schueren, H, Van den Berghe, J J, Cassiman   +3 more
openaire   +2 more sources

Ciliogenesis following salpingostomy of rabbit hydrosalpinges

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1984
Twenty-five artificially induced hydrosalpinges were studied in New Zealand white rabbits. Hydrosalpinges had been created after 2-16 wk occlusion of both the fimbrial end and the ampullary isthmic junction (A.I.J.), using either Ethilon 8/0 or tantalum clips. Their diameters ranged from 4 to 12 mm, being larger in the clipped oviducts.
G, Vásquez, H, Vemer, W, Boeckx, I A, Brosens   +3 more
openaire   +2 more sources

Ciliogenesis of The Retinal Photoreceptor

Proceedings, annual meeting, Electron Microscopy Society of America, 1980
Development of the modified cilium in rod photoreceptors is unique in that, unlike other ciliated epithelia, the photoreceptor cilium does not project into a free lumen but rather abuts against the apex of another epithelial cell, i.e. pigmented epithelium.
Jack V. Greinert, H. Daniel Bodley, Thomas A. Weidman   +2 more
openaire   +1 more source

Ciliogenesis in photoreceptor cells of the retina

Experimental Eye Research, 1981
Ciliogenesis in the retinal photoreceptor of fetal, neonatal and adult ferrets has been investigated by electron microscopy. Ciliogenesis is described from the time (prenatal day 21) when a diplosome (two centrioles) is observed migrating toward the region of the external limiting membrane prior to eventual alignment beneath the apical plasma membrane ...
J V, Greiner, T A, Weidman, H D, Bodley, C A, Greiner   +3 more
openaire   +2 more sources

Dynein‐2 and ciliogenesis in Tetrahymena

Cell Motility, 2009
AbstractDynein‐2 is the motor responsible for retrograde intraflagellar transport. In situ, dynein‐2 comprises four subunits: the dynein‐2 heavy chain (DYH2); the dynein‐2 intermediate chain; the dynein‐2 light‐intermediate chain (D2LIC); and dynein light chain 8 (Rompolas et al. 2007. Chlamydomonas FAP133 is a dynein intermediate chain associated with
David J, Asai, Vidyalakshmi, Rajagopalan, David E, Wilkes   +2 more
openaire   +2 more sources

Promoting Ciliogenesis with a Prostaglandin

Science Signaling, 2014
Export of PGE 2 by the transporter ABCC4 promotes cilia formation.
openaire   +1 more source