Results 131 to 140 of about 34,354 (355)

A boundary element regularised Stokeslet method applied to cilia and flagella-driven flow [PDF]

, 2009
A boundary element implementation of the regularised Stokeslet method of Cortez is applied to cilia and flagella-driven flows in biology. Previously-published approaches implicitly combine the force discretisation and the numerical quadrature used to ...
Burgers J. M., Gray J., Sanderson M. J.
core   +1 more source

A viscoelastic traction layer model of mucociliary flow [PDF]

, 2007
A new mathematical model of the transport of mucus and periciliary liquid (PCL) in the airways by cilia is presented. Mucus is represented by a linearly viscoelastic fluid, the mat of cilia is modelled as an ‘active porous medium.’ The propulsive effect ...
Blake, J R, Gaffney, E. A., Lubkin, D J, Smith, D J   +3 more
core   +1 more source

The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium

Communications Biology
The efficient transport of proteins into the primary cilium is a crucial step for many signaling pathways. Dysfunction of this process can lead to the disruption of signaling cascades or cilium assembly, resulting in developmental disorders and cancer ...
S. M. Niedziółka, S. Datta, T. Uśpieński, B. Baran, W. Skarżyńska, E. W. Humke, R. Rohatgi, P. Niewiadomski   +7 more
doaj   +1 more source

Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors

Frontiers in Molecular Neuroscience, 2018
Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals.
Celine Brooks, Joseph Murphy, Marycharmain Belcastro, Daniel Heller, Saravanan Kolandaivelu, Oleg Kisselev, Maxim Sokolov, Maxim Sokolov   +7 more
doaj   +1 more source

Biological Fluid Mechanics Under the Microscope: A Tribute to John Blake

, 2018
John Blake (1947--2016) was a leader in fluid mechanics, his two principal areas of expertise being biological fluid mechanics on microscopic scales and bubble dynamics. He produced leading research and mentored others in both Australia, his home country,
Smith, David J.
core   +1 more source

New phagotrophic euglenoid species (new genus Decastava; Scytomonas saepesedens; Entosiphon oblongum), Hsp90 introns, and putative euglenoid Hsp90 pre-mRNA insertional editing [PDF]

, 2015
We describe three new phagotrophic euglenoid species by light microscopy and 18S rDNA and Hsp90 sequencing: Scytomonas saepesedens; Decastava edaphica; Entosiphon oblongum. We studied Scytomonas and Decastava ultrastructure.
Cavalier-Smith, Thomaa, Chao, Ema E., Vickerman, Keith   +2 more
core   +1 more source

Hedgehog Signaling and the Cilium: in the Zone [PDF]

Developmental Cell, 2012
Hedgehog signaling is transduced at the primary cilium, but the precise mechanisms underlying this action are not clear. In this issue of Developmental Cell, Dorn and colleagues (2012) describe a novel mechanism for control of Hedgehog signaling by Evc proteins within the primary cilium.
openaire   +3 more sources

A New EP300‐Related Syndrome With Prominent Developmental and Immune Phenotypes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Rubinstein Taybi syndrome (RTS) is a disorder of chromatin remodeling and transcriptional regulation caused by heterozygous pathogenic variants in CREBBP and EP300. RTS is characterized by a distinct facial gestalt, intellectual disability, structural kidney and heart differences, feeding difficulties, and broad thumbs and great toes ...
Devi Priyanka Maripuri, Jessica Gold, Nina Gold, Alanna Strong   +3 more
wiley   +1 more source

Rebuilding ships while at sea—Character individuality, homology, and evolutionary innovation

Journal of Morphology, Volume 284, Issue 1, January 2023., 2023
Building on a previous account of evolutionary innovation, I propose here that evolutionary novelties are those individualized characters that are not homologous to any characters in the ancestor. Integrating functional and structural perspectives, I argue that functional as well as structural considerations are important for character ...
Gerhard Schlosser
wiley   +1 more source

Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys

Frontiers in Physiology, 2017
Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo, Juan Chen, Jasmine Sardar, Rinzhin T. Sherpa, Rajasekharreddy Pala, Kimberly F. Atkinson, William J. Pearce, Lubo Zhang, Surya M. Nauli, Surya M. Nauli   +9 more
doaj   +1 more source