Results 121 to 130 of about 39,977 (306)
A porous prolate-spheroidal model for ciliated micro-organisms [PDF]
, 1977 A fluid-mechanical model is developed for representing the mechanism of propulsion of a finite ciliated micro-organism having a prolate-spheroidal shape.
Keller, Stuart R., Wu, Theodore Y.
core +1 more source
Kinematics of the Most Efficient Cilium
Physical Review Letters, 2012 4 pages, 5 ...
Christophe Eloy, Eric Lauga
openaire +4 more sources
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Cell-wide arrangement of Golgi/RE units depends on the microtubule organization
Cell Structure and FunctionWe have previously shown that Golgi stacks and recycling endosomes (REs) exist as Golgi/RE units in sea urchin embryos. In this study, we showed that Golgi/RE units were scattered throughout the cytoplasm at early developmental stages but gathered to ...
Tatsuya Tago +9 more
doaj +1 more source
The 1/N Expansion of Tensor Models Beyond Perturbation Theory
, 2013 We analyze in full mathematical rigor the most general quartically perturbed invariant probability measure for a random tensor. Using a version of the Loop Vertex Expansion (which we call the mixed expansion) we show that the cumulants write as explicit ...
Gurau, Razvan
core +1 more source
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
Advanced Science, EarlyView.. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
Frontiers in Cell and Developmental BiologyCilia and flagella associated protein 410 (CFAP410) is a protein localized at the basal body of cilia/flagella and plays essential roles in ciliogenesis. Multiple single amino acid mutations in CFAP410 have been identified in patients.
Alexander Stadler +18 more
doaj +1 more source
Advanced Science, EarlyView.A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui +9 more
wiley +1 more source
Unexpected encounter with an intracameral cilium postcataract surgery
The Pan-American Journal of OphthalmologyBackground: Cataract surgery, a routine and highly successful ophthalmic intervention, is not immune to unexpected challenges. While complications are infrequent, their diverse nature necessitates a thorough understanding to ensure optimal patient ...
Anchal Tripathi +4 more
doaj +1 more source
Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair
Advanced Science, EarlyView.This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar +9 more
wiley +1 more source