The Primary Cilium is a Self-Adaptable, Integrating Nexus for Mechanical Stimuli and Cell Signaling [PDF]
, 2015 An M. Nguyen +2 more
openalex +1 more source
Mimicking Life: Autonomous Oscillating Artificial Cilia Driven by Chemical Power
Advanced Intelligent Systems, EarlyView.The synthesis and motion analysis of chemically actuated, individually autonomous artificial cilia are presented. Driven by an internal chemical reaction, the self‐driven individual cilia require no external stimuli. They undergo periodic oscillatory motion with a 3D beat pattern and exhibit chemotactic shifts, reminiscent of biological systems.
Rajata Suvra Chakrovorty +2 more
wiley +1 more source
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function [PDF]
, 2014 Irene Franco +18 more
openalex +1 more source
Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning
Advanced Intelligent Systems, EarlyView.A fundamental mucus cleaning mechanism is reported, which utilizes both artificial cilia mechanical sweeping and suction‐based mucus cleaning. A novel haptic feedback interface for the artificial cilia provides touch feedback on tissue contact, enhancing operator control and safety.
Zhongming Lyu +7 more
wiley +1 more source
Pyridine Into Pyrrole Transformation Induced Within the Confinement of the Macrocycle
Angewandte Chemie, EarlyView.This work demonstrates the nontrivial reactivity of pyridine incorporated into a porphyrin framework. The most significant achievement is the contraction of the six‐membered ring to a pyrrole ring, which is a phenomenon of great interest to researchers in this field.
Paulina Krzyszowska +5 more
wiley +2 more sources
Ciliary propulsion of objects in tubes: wall drag on swimming Tetrahymena (Ciliata) in the presence of mucin and other long-chain polymers [PDF]
, 1976 The lubrication effect of three long-chain polymers - mucin, methylcellulose and Ficoll - on ciliary propulsion in tubes is measured by plotting the relative velocities of swimming cilitates as a function of the tube bore diameter.
Winet, H.
core
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim +9 more
wiley +1 more source
Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle +26 more
wiley +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson +8 more
wiley +1 more source
Deciphering vesicle-assisted transport mechanisms in cytoplasm to cilium trafficking
Frontiers in Cellular NeuroscienceThe cilium, a pivotal organelle crucial for cell signaling and proper cell function, relies on meticulous macromolecular transport from the cytoplasm for its formation and maintenance.
Mark Tingey +3 more
doaj +1 more source