Results 171 to 180 of about 22,757 (263)

A new species and a synonym in Centaurea sect. Microlophus (Asteraceae, Cardueae–Centaureinae) from the Khuzestan Province, southwestern Iran

Nordic Journal of Botany, EarlyView.
A new species, Centaurea baghmalekensis Negaresh (Asteraceae) in C. sect. Microlophus (Cass.) DC., is described and illustrated from the Khuzestan Province, southwestern Iran. The new species is morphologically most similar to Centaurea pabotii Wagenitz, a recently described species from the Khuzestan Province.
Kazem Negaresh
wiley   +1 more source

Glucagon secretion by pancreatic alpha-cells requires an intact tubulin-cytoskeleton-primary cilium axis. [PDF]

Mol Med
Casanueva-Álvarez E, Sanz-González A, Vilas A, Cámara-Torres P, Ravier MA, Eslava-Alcon S, Duran-Ruiz MC, Ramírez CM, Petropoulou PI, Rodriguez-Calvo T, Merino B, Perdomo G, Cozar-Castellano I.   +12 more
europepmc   +1 more source

Unshared on the top: strong segregation of pathogen communities between western honey bees and wild bees in a retreating glacier foreland

Oikos, EarlyView.
Shared flowers can facilitate pathogen transmission between managed honey bees and wild bees, yet this process remains poorly understood in ecosystems undergoing rapid environmental change. Using a glacier foreland in Switzerland, we present the first study on how glacier retreat stages and bee life‐history traits influence pathogen occurrence across ...
Andrea Ferrari, Giovanni Cilia, Matteo Conti, Bao Ngan Tu, Nora Khelidj, Gianalberto Losapio, Carlo Polidori   +6 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Altered ciliary morphology reduces mechanosensation in a cystic kidney model as indicated by a mathematical model. [PDF]

Sci Rep
Kumamoto K, Kagami H, Saitoh S, Yamada S, Matsumoto M, Ohno N.   +5 more
europepmc   +1 more source

Respiratory profile of pediatric patients undergoing hematopoietic stem cell transplantation studied by oscillometry – A TRANSPIRE cohort

Pediatric Investigation, EarlyView.
These are results from a multi‐center collaboration between four large pediatric institutions, investigating baseline respiratory system function in a cohort of children undergoing hematopoietic stem cell transplantation. This manuscript proposes respiratory oscillometry as a novel way to prospectively follow lung function in these children.
Maureen B. Parenti, Julian Allen, Lisa R. Young, Heather Boas, Jason Freedman, Christopher Towe, Jane Koo, Kasiani Myers, Jason C. Woods, Adam Lane, Jonathan Gaffin, Wai Wong, Leslie Lehmann, Fernando Urrego, Gabriel Salinas Cisneros, Matthew F. Abts, K. Scott Baker, Manuel Silva‐Carmona, Erin Doherty, Paul D. Robinson, Margaret MacMillan, Stella M. Davies, Samuel B. Goldfarb   +22 more
wiley   +1 more source

Primary Cilium Forces Neuroendocrine Shift in Prostate Cancer through YAP1 Repression and Reduced Mitochondrial Activity. [PDF]

Theranostics
Guo Y, Peng S, Jamet T, Firlej V, Irondelle M, Nau C, Girard CA, Asrani K, Lotan TL, Huc R, Soyeux P, Rouleau M, Lacas-Gervais S, Rovini A, Luciano S, Humbert O, Schiappa R, Pujalte-Martin M, Vigneau M, Peraldi P, Bost F, Lazennec G, Vacherot F, Mazure NM.   +23 more
europepmc   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

PROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar, Anna Battenhouse, Andrew J. Kim, Sung‐Eun Kim   +3 more
wiley   +1 more source

<i>Astragalus</i> small molecules protect BMSCs from radiation-induced bystander effect and enhance lung cancer radiosensitivity via the primary cilium/TGF-βR1/Smad3 pathway. [PDF]

Front Oncol
Miao Z, Wu M, Dai S, Wang X, Li YY, Liu F, Liu Z, Zhang L, Liu Y.   +8 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source