Results 191 to 200 of about 40,089 (306)

Loss of a primary cilium in PDAC [PDF]

Cell Cycle, 2017
Tetsuo, Kobayashi, Hiroshi, Itoh
openaire   +2 more sources

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

The P23H Rhodopsin Mouse Model Reveals a Novel Interaction Between the Endoplasmic Reticulum and Connecting Cilium Rootlet Within Photoreceptors. [PDF]

Invest Ophthalmol Vis Sci
Novoselov SS, Mendes BS, Martello A, Wavre-Shapton S, Aguila M, Guarascio R, Ziaka K, Bevilacqua D, Metodieva G, Luthert PJ, Yang J, Metodiev MV, Reeves PJ, Futter CE, Cheetham ME, Burgoyne T.   +15 more
europepmc   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Gene signature linked to inhaled corticosteroid-induced lung function improvement in COPD: insights from the GLUCOLD Study. [PDF]

ERJ Open Res
Zhang J, van den Berge M, Brandsma CA, Timens W, Faiz A, Hylkema MN, de Vries M.   +6 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Editorial: Molecular mechanisms of cilia related diseases

Frontiers in Molecular Biosciences
Sara Carvalhal, Sara Carvalhal, Bruno Carmona, Bruno Carmona, Anne-Marie Tassin, João Gonçalves   +5 more
doaj   +1 more source

Compartmentalized Nutrient and Hormone Sensing in β-Cells: the Role of Primary Cilia. [PDF]

Physiology (Bethesda)
Hughes JW, Merrins MJ.
europepmc   +1 more source

Exploring the Use and Impact of Composite Materials in Robotics: A Systematic Review

Journal of Field Robotics, EarlyView.
ABSTRACT Lightweight and high‐strength materials are important in robotics, as structural design impacts efficiency, payload capacity, and energy consumption. Composite materials, with their superior stiffness‐to‐weight ratios and multifunctional properties, offer clear advantages over conventional metals and polymers.
Doglas Negri, Gabriela Wessling Oening, Felipe Augusto Carvalho de Faria, Sarah Maria Schroeder, Ricardo De Medeiros   +4 more
wiley   +1 more source

Cytokinetic abscission failures in a polarized epithelium affect apical membrane size and cilia. [PDF]

Mol Biol Cell
Lettieri KS, McNeely KC, Dwyer ND.
europepmc   +1 more source