Results 211 to 220 of about 40,089 (306)

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

A high-resolution spatial map of cilia-associated proteins in the human fallopian tube. [PDF]

Nat Commun
Hikmet F, Digre A, Hansen JN, Schon SB, Lundberg E, Olovsson M, Uhlén M, Méar L, Lindskog C.   +8 more
europepmc   +1 more source

Risk Factors and Predictive Model for Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma: A Retrospective Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the impact of different radiation fields on the risk of otitis media with effusion (OME) in nasopharyngeal carcinoma (NPC) patients and to develop a nomogram to identify high‐risk patients after radiotherapy. Methods Clinical data were collected from 170 NPC patients who underwent radiotherapy at Peking Union Medical ...
Zhi‐Jin Han, Shu Wang, Shu‐Yi Wang, Zhi‐Yuan Wu, Meng‐Yao Xie, Chen Li, Qi Tang, Xiao‐Wu Huang, Yu‐Liang Sun, Xin‐Hai Wang, Ke Hu, Hua Yang   +11 more
wiley   +1 more source

Phosphatidylinositol 4,5-bisphosphate impacts extracellular vesicle shedding from C. elegans ciliated sensory neurons. [PDF]

J Cell Sci
Elsayyid MW, Semmel AE, Parekh KD, Prova NS, Ke T, Tanis JE.   +5 more
europepmc   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source

Primary cilia function as hubs for signal transduction. [PDF]

Cell Biosci
Li B, He YY, Yang ZM.
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Centrosomal JAK2 Tyrosine Kinase Regulates Primary Cilia Length, Cell Proliferation, and Cilia Orientation During Cell Migration. [PDF]

FASEB J
Karki G, Boone L, Klaiber T, Lambert T, Kimball B, Burkhart B, Youssef M, Diakonova M.   +7 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

New Insights into the Molecular Actions of Grosheimin, Costunolide, and α- and β-Cyclocostunolide on Primary Cilia Structure and Hedgehog Signaling. [PDF]

Int J Mol Sci
Murillo-Pineda M, Martínez-Miralles J, Medina-Calzada Z, Varela RM, Macías FA, Chinchilla N, Juárez-Soto Á, Santpere G, Reales E.   +8 more
europepmc   +1 more source