Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes in C. elegans. [PDF]
Nikonorova IA+6 more
europepmc +1 more source
Genetic Risk Factors in Normal Pressure Hydrocephalus: What We Know and What Is Next
Abstract Knowledge of the genetic factors in normal pressure hydrocephalus (NPH) is rapidly evolving, with significant advances in recent years. We conducted a systematic review examining genetic contributions to NPH risk. Ovid Embase, Ovid Medline, Web of Science, and Cochrane Central were searched from inception through October 14, 2024, for human ...
Camila C. Piccinin+9 more
wiley +1 more source
NEK8, a NIMA-family protein kinase at the core of the ciliary INV complex. [PDF]
Roig J.
europepmc +1 more source
The primary cilium: a signalling centre during vertebrate development
Sarah C. Goetz, Kathryn V. Anderson
openalex +2 more sources
The Primary Cilium as a Novel Extracellular Sensor in Bone [PDF]
David A. Hoey+2 more
openalex +1 more source
Somatostatin triggers local cAMP and Ca<sup>2+</sup> signaling in primary cilia to modulate pancreatic β-cell function. [PDF]
Nilsson CI+7 more
europepmc +1 more source
Kinesin-2 family motors in the unusual photoreceptor cilium [PDF]
Jarema Malicki, Joseph C. Besharse
openalex +1 more source
Evaluating Adverse Outcomes After Myringotomy or Tube Placement in Head and Neck Cancer
Abstract Objective Evaluate rates of adverse outcomes among patients with a history of head and neck cancer undergoing myringotomy with or without tube placement for middle ear effusion. Study Design Retrospective chart review. Setting Academic medical center.
Krithika Kuppusamy+7 more
wiley +1 more source
The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to the base of primary cilia. [PDF]
Linnert J+5 more
europepmc +1 more source
Evaluation of Benzo[cd]indol‐2(1H)‐ones as Downstream Hedgehog Pathway Inhibitors
Benzo[cd]indol‐2(1H)‐one 1 inhibits the Hedgehog signaling pathway downstream of Suppressor of Fused, lowering cellular and ciliary GLI2 levels, and preventing GLI1 expression. A PROTAC‐based competition assay validated the cellular engagement of BET bromodomains, adding compound 1 to the growing set of epigenetic modulators of the Hedgehog signaling ...
Ioannis A. Tsakoumagkos+8 more
wiley +1 more source