Results 241 to 250 of about 40,089 (306)

Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models

Andrology, EarlyView.
ABSTRACT Background Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research on each factor individually, their combined pathological effects remain poorly understood.
Yunlong Yao, Xi Zhang, Lingru Li, Yunzhi Zhang, Shuo Huang, Yulin Zong, Mingrui Li, Fufangyu Zhao, Linghui Zhu, Tianxing Li, Wenlong Sun, Mingyan Shao, Yanfei Zheng   +12 more
wiley   +1 more source

In vitro approaches to study centriole and cilium function in early mouse embryogenesis. [PDF]

Life Sci Alliance
Voelkl I, Civetta T, Egg M, Huber M, Feng S, Dammermann A, Buecker C.   +6 more
europepmc   +1 more source

Development of a Swine Whole Eye Transplant Ex Vivo Perfusion Protocol

Artificial Organs, EarlyView.
This study establishes the first subnormothermic machine perfusion protocol for whole eye transplants in a swine model, enabling up to 18 h of preservation with stable metabolic function, limited edema, and recovery of mydriasis. ABSTRACT Background The first human Whole Eye Transplant (WET) has sparked new hope for patients who have lost vision due to
Haïzam Oubari, Lucile Cabanel, Yanis Berkane, Ali Mojallal, Mark A. Randolph, Basak Uygun, Korkut Uygun, Curtis L. Cetrulo Jr., Alexandre G. Lellouch   +8 more
wiley   +1 more source

Cilia Dynamics in Primary Ciliary Dyskinesia: A Biophysical Characterization of the <i>RSPH4A</i> Founder Variant. [PDF]

Cells
Rosario-Ortiz G, Muñiz-Hernández J, Ortiz-Pérez NM, Ramos-Benitez MJ, Mosquera RA, De Jesús-Rojas W.   +5 more
europepmc   +1 more source

The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023

Acta Ophthalmologica, EarlyView.
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg, Jenny Gyllén, Birgitte Haargaard, Alf Nyström, Arzu Karatepe Hashas, Anna Linnarsson Wiklund, Eric Trocmé, Ulrika Kjellström, Kristina Tornqvist, Gunilla Magnusson   +9 more
wiley   +1 more source

Bi-allelic variants in FSD1L cause a neurodevelopmental disorder overlapping with L1 syndrome. [PDF]

Am J Hum Genet
Serpieri V, Vezain-Mouchard M, Orsi A, Lecointre M, Mazzotta C, Marguet F, Garbelli A, Marcorelles P, Celli L, Goldenberg A, De Mori R, Drouot N, Petrizzelli F, Janin F, Nicolas G, Smal N, Condoluci C, Marini C, Tran-Mau-Them F, Ruault V, Micalizzi A, Bione S, Mazza T, Pichiecchio A, Ginevrino M, Weckhuysen S, Bedois A, Desnous B, Hermitte L, Rabie G, Kanaan M, Gonzalez BJ, Sabbioneda S, Laquerrière A, Saugier-Veber P, Valente EM.   +35 more
europepmc   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source

In-depth analysis of obesity-associated changes in adipose tissue-derived mesenchymal stromal/stem cells and primary cilia function. [PDF]

Commun Biol
Kreis NN, Friemel A, Ritter A, Hentrich AE, Siebelitz E, Louwen F, Yuan J.   +6 more
europepmc   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg, Jithmi Weliwitage, Marie von Berg, Silvia Schrittenlocher, Simona Schlereth, Claus Cursiefen, Björn Bachmann   +6 more
wiley   +1 more source

Three-dimensional beating pattern of the ciliary tip in the live ciliate Tetrahymena. [PDF]

J Cell Sci
Marumo A, Ishii H, Yamaguchi S, Sumiyoshi R, Matsuda K, Yamagishi M, Yajima J.   +6 more
europepmc   +1 more source