Results 71 to 80 of about 34,354 (355)
Minimal design of a synthetic cilium [PDF]
Physical Review ResearchWe study a slender filament beating in a viscous fluid with novel curvature-dependent bending stiffness. Our numerical and experimental investigations reveal that such differential stiffness can sustain planar bending waves far along flexible filaments, in stark contrast to the uniform-stiffness case which requires more sophisticated control.
Clément Moreau +6 more
openaire +4 more sources
Biology Open, 2021 Ciliary motility is powered by a suite of highly conserved axoneme-specific dynein motor complexes. In humans, the impairment of these motors through mutation results in the disease primary ciliary dyskinesia (PCD).
Petra zur Lage +7 more
doaj +1 more source
Point torque representations of ciliary flows [PDF]
arXiv, 2023 Ciliary flows are generated by a vast array of eukaryotic organisms, from unicellular algae to mammals, and occur in a range of different geometrical configurations. We employ a point torque -- or `rotlet' -- model to capture the time-averaged ciliary flow above a planar rigid wall. We demonstrate the advantages (i.e.
arxiv
Finding the ciliary beating pattern with optimal efficiency [PDF]
Proc. Natl. Acad. Sci. USA 108: 15727-15732 (2011), 2011 We introduce a measure for energetic efficiency of biological cilia acting individually or collectively and numerically determine the optimal beating patterns according to this criterion. Maximizing the efficiency of a single cilium leads to curly, often symmetric and somewhat counterintuitive patterns.
arxiv +1 more source
Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation [PDF]
, 2015 Funded by Marie Curie Intra European Fellowship (GENOMICDIFF) Wellcome Trust ...
Chapple, JP +4 more
core +1 more source
Role for the IFT-A Complex in Selective Transport to the Primary Cilium
Cell Reports, 2016 Intraflagellar transport sub-complex A (IFT-A) is known to regulate retrograde IFT in the cilium. To rigorously assess its other possible roles, we knocked out an IFT-A subunit, IFT121/WDR35, in mammalian cells and screened the localization of more than ...
Wenxiang Fu +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Surface‐attached multilayer micromagnet systems are fabricated by two‐photon crosslinking. The pillar‐shaped micro actuators consist of a soft and flexible surface‐attached cell‐repellent hydrogel layer at the bottom, acting as a hinge and a cell‐adhesive hydrophobic polymer filled with magnetic nanoparticles.
Nicolas Geid +5 more
wiley +1 more source
Predicting the locations of force-generating dyneins in beating cilia and flagella
Frontiers in Cell and Developmental Biology, 2022 Cilia and flagella are slender cylindrical organelles whose bending waves propel cells through fluids and drive fluids across epithelia. The bending waves are generated by dynein motor proteins, ATPases whose force-generating activity changes over time ...
Jonathon Howard +7 more
doaj +1 more source
Fluid transport at low Reynolds number with magnetically actuated artificial cilia [PDF]
, 2008 By numerical modeling we investigate fluid transport in low-Reynolds-number flow achieved with a special elastic filament or artifical cilium attached to a planar surface. The filament is made of superparamagnetic particles linked together by DNA double strands.
arxiv +1 more source
Metachronal motion of artificial magnetic cilia [PDF]
Soft Matter, 2018,14, 3689-3693, 2018 Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling waves propagating along ciliary carpet.
arxiv +1 more source