Results 51 to 60 of about 29,037 (298)
Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage [PDF]
, 2014 Primary cilia are slender, microtubule based structures found in the majority of cell types with one cilium per cell. In articular cartilage, primary cilia are required for chondrocyte mechanotransduction and the development of healthy tissue.
Ramaswamy, G +7 more
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Design and Fabrication of an Integrated Hollow Concave Cilium MEMS Cardiac Sound Sensor
Micromachines, 2022 In light of a need for low-frequency, high sensitivity and broadband cardiac murmur signal detection, the present work puts forward an integrated MEMS-based heart sound sensor with a hollow concave ciliary micro-structure. The advantages of a hollow MEMS
Bo Wang +9 more
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Frontiers in Genetics, 2022 Lung adenocarcinoma (LUAD) has become the most prevalent histologic subset of primary lung cancer, and effective innovative prognostic models are needed to enhance the feasibility of targeted therapies for the disease.
Huizhe Zhang +7 more
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A Ciliary View of the Immunological Synapse
Cells, 2019 The primary cilium has gone from being a vestigial organelle to a crucial signaling hub of growing interest given the association between a group of human disorders, collectively known as ciliopathies, and defects in its structure or function.
Chiara Cassioli, Cosima T. Baldari
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Types of centrioles and cilium.
, 2022 Types of centrioles and cilium.
Katsuhiko Ono (293663) +7 more
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Compartmentalised cAMP signalling in the primary cilium [PDF]
, 2023 cAMP is a universal second messenger that relies on precise spatio-temporal regulation to control varied, and often opposing, cellular functions. This is achieved via selective activation of effectors embedded in multiprotein complexes, or signalosomes ...
Manuela Zaccolo, Ester Paolocci
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Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys
Frontiers in Physiology, 2017 Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo +9 more
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Emerging Roles of Primary Cilia in Glioma
Frontiers in Cellular Neuroscience, 2019 Primary cilia are microtubule-based organelles that are typically present on cells during the G0 or G1-S/G2 phases of the cell cycle. Recent studies of glioblastoma (GBM) biopsies, a brain tumor that is notorious for its aggressive growth and resistance ...
Matthew R. Sarkisian +2 more
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Comparative Biology of Centrosomal Structures in Eukaryotes
Cells, 2018 The centrosome is not only the largest and most sophisticated protein complex within a eukaryotic cell, in the light of evolution, it is also one of its most ancient organelles.
Ralph Gräf
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Dissecting the Vesicular Trafficking Function of IFT Subunits
Frontiers in Cell and Developmental Biology, 2020 Intraflagellar transport (IFT) was initially identified as a transport machine with multiple protein subunits, and it is essential for the assembly, disassembly, and maintenance of cilium/flagellum, which serves as the nexus of extracellular-to ...
Huihui Yang, Huihui Yang, Kaiyao Huang
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