Results 41 to 50 of about 6,760 (249)

Assembling a primary cilium [PDF]

open access: yesCurrent Opinion in Cell Biology, 2013
Cilia are evolutionarily conserved, membrane-bound, microtubular projections emanating from the cell surface. They are assembled on virtually all cell types in the human body, with very few exceptions, and several recent reviews have covered the topic in great detail.
Sehyun, Kim, Brian David, Dynlacht
openaire   +2 more sources

A recombinant BBSome core complex and how it interacts with ciliary cargo

open access: yeseLife, 2017
Cilia are small, antenna-like structures on the surface of eukaryotic cells that harbor a unique set of sensory proteins, including GPCRs and other membrane proteins.
Björn Udo Klink   +5 more
doaj   +1 more source

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

open access: yeseLife, 2023
Cilia, either motile or non-motile (a.k.a primary or sensory), are complex evolutionarily conserved eukaryotic structures composed of hundreds of proteins required for their assembly, structure and function that are collectively known as the ciliome ...
Rebeca Brocal-Ruiz   +7 more
doaj   +1 more source

Trafficking in and to the primary cilium [PDF]

open access: yesCilia, 2012
Abstract Polarized vesicle trafficking is mediated by small GTPase proteins, such as Rabs and Arls/Arfs. These proteins have essential roles in maintaining normal cellular function, in part, through regulating intracellular trafficking. Moreover, these families of proteins have recently been implicated in the formation and function of the ...
Hsiao, Yi-Chun   +2 more
openaire   +2 more sources

A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

open access: yeseLife, 2015
Small G-proteins of the ADP-ribosylation-factor-like (Arl) subfamily have been shown to be crucial to ciliogenesis and cilia maintenance. Active Arl3 is involved in targeting and releasing lipidated cargo proteins from their carriers PDE6δ and UNC119a/b ...
Katja Gotthardt   +5 more
doaj   +1 more source

Design and Implementation of a Composite Hydrophone of Sound Pressure and Sound Pressure Gradient

open access: yesMicromachines, 2021
The bionic cilium MEMS vector hydrophone has the characteristics of low power consumption, small volume, and good low-frequency response. Nevertheless, there exists the problem of left–right ambiguity in the azimuth estimation of a single hydrophone.
Guojun Zhang   +6 more
doaj   +1 more source

Cep164, a novel centriole appendage protein required for primary cilium formation [PDF]

open access: yes, 2007
Primary cilia (PC) function as microtubule-based sensory antennae projecting from the surface of many eukaryotic cells. They play important roles in mechano- and chemosensory perception and their dysfunction is implicated in developmental disorders and ...
Graser, Susanne   +20 more
core   +1 more source

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation [PDF]

open access: yes, 2015
Funded by Marie Curie Intra European Fellowship (GENOMICDIFF) Wellcome Trust ...
Thorpe, SD   +4 more
core   +1 more source

Ciliary Dyneins and Dynein Related Ciliopathies

open access: yesCells, 2021
Although ubiquitously present, the relevance of cilia for vertebrate development and health has long been underrated. However, the aberration or dysfunction of ciliary structures or components results in a large heterogeneous group of disorders in ...
Dinu Antony   +2 more
doaj   +1 more source

In-phase and anti-phase flagellar synchronization by waveform compliance and basal coupling

open access: yesNew Journal of Physics, 2017
We present a theory of flagellar synchronization in the green alga Chlamydomonas , using full treatment of flagellar hydrodynamics and measured beat patterns.
Gary S Klindt   +3 more
doaj   +1 more source

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