Results 21 to 30 of about 22,757 (263)

Design and Fabrication of an Integrated Hollow Concave Cilium MEMS Cardiac Sound Sensor

open access: yesMicromachines, 2022
In light of a need for low-frequency, high sensitivity and broadband cardiac murmur signal detection, the present work puts forward an integrated MEMS-based heart sound sensor with a hollow concave ciliary micro-structure. The advantages of a hollow MEMS
Bo Wang   +9 more
doaj   +1 more source

Assembling a primary cilium [PDF]

open access: yesCurrent Opinion in Cell Biology, 2013
Cilia are evolutionarily conserved, membrane-bound, microtubular projections emanating from the cell surface. They are assembled on virtually all cell types in the human body, with very few exceptions, and several recent reviews have covered the topic in great detail.
Sehyun, Kim, Brian David, Dynlacht
openaire   +2 more sources

Trainspotting in a cilium

open access: yeseLife, 2017
A new imaging technique sheds light on how cilia regulate their length and growth.
Dhivya Kumar, Stephen M King
openaire   +3 more sources

The Primary Cilium of Adipose Progenitors Is Necessary for Their Differentiation into Cancer-Associated Fibroblasts that Promote Migration of Breast Cancer Cells In Vitro

open access: yesCells, 2020
Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs).
Pascal Peraldi   +3 more
doaj   +1 more source

Cilium assembly and disassembly [PDF]

open access: yesNature Cell Biology, 2016
The primary cilium is an antenna-like, immotile organelle present on most types of mammalian cells, which interprets extracellular signals that regulate growth and development. Although once considered a vestigial organelle, the primary cilium is now the focus of considerable interest.
Irma, Sánchez, Brian David, Dynlacht
openaire   +2 more sources

A novel defined cuproptosis-related gene signature for predicting the prognosis of lung adenocarcinoma

open access: yesFrontiers in Genetics, 2022
Lung adenocarcinoma (LUAD) has become the most prevalent histologic subset of primary lung cancer, and effective innovative prognostic models are needed to enhance the feasibility of targeted therapies for the disease.
Huizhe Zhang   +7 more
doaj   +1 more source

A recombinant BBSome core complex and how it interacts with ciliary cargo

open access: yeseLife, 2017
Cilia are small, antenna-like structures on the surface of eukaryotic cells that harbor a unique set of sensory proteins, including GPCRs and other membrane proteins.
Björn Udo Klink   +5 more
doaj   +1 more source

A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

open access: yeseLife, 2015
Small G-proteins of the ADP-ribosylation-factor-like (Arl) subfamily have been shown to be crucial to ciliogenesis and cilia maintenance. Active Arl3 is involved in targeting and releasing lipidated cargo proteins from their carriers PDE6δ and UNC119a/b ...
Katja Gotthardt   +5 more
doaj   +1 more source

In-phase and anti-phase flagellar synchronization by waveform compliance and basal coupling

open access: yesNew Journal of Physics, 2017
We present a theory of flagellar synchronization in the green alga Chlamydomonas , using full treatment of flagellar hydrodynamics and measured beat patterns.
Gary S Klindt   +3 more
doaj   +1 more source

Dissecting the Vesicular Trafficking Function of IFT Subunits

open access: yesFrontiers in Cell and Developmental Biology, 2020
Intraflagellar transport (IFT) was initially identified as a transport machine with multiple protein subunits, and it is essential for the assembly, disassembly, and maintenance of cilium/flagellum, which serves as the nexus of extracellular-to ...
Huihui Yang, Huihui Yang, Kaiyao Huang
doaj   +1 more source

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