Results 61 to 70 of about 22,757 (263)
Advanced Robotics Research, EarlyView.Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin +3 more
wiley +1 more source
Emerging Roles of Primary Cilia in Glioma
Frontiers in Cellular Neuroscience, 2019 Primary cilia are microtubule-based organelles that are typically present on cells during the G0 or G1-S/G2 phases of the cell cycle. Recent studies of glioblastoma (GBM) biopsies, a brain tumor that is notorious for its aggressive growth and resistance ...
Matthew R. Sarkisian +2 more
doaj +1 more source
Advanced Science, 2022 Retinopathy of prematurity (ROP) is one of the leading causes of childhood visual impairment and blindness. However, there are still very few effective pharmacological interventions for ROP.
Jie Ran +13 more
doaj +1 more source
Development and disease of the photoreceptor cilium [PDF]
Clinical Genetics, 2009 Primary cilia are microtubule‐rich hair‐like extensions protruding from the surface of most post‐mitotic cells. They act as sensory organelles that help interpret various environmental cues. Mutations in genes encoding proteins involved in ciliogenesis or protein transport to the primary cilia lead to a wide variety of diseases commonly referred to as ...
Ramamurthy, V., Cayouette, M.
openaire +3 more sources
Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Advanced Robotics Research, EarlyView.Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Communications BiologyThe dual-specificity tyrosine-phoshorylation-regulated kinase (DYRK) family are multifunctional enzymes crucial for diverse cellular processes, including signaling through the primary cilium. Their dysregulation has been implicated in various cancers and
Melis D. Arslanhan +2 more
doaj +1 more source
Proteomic analysis of a eukaryotic cilium [PDF]
The Journal of Cell Biology, 2005 Cilia and flagella are widespread cell organelles that have been highly conserved throughout evolution and play important roles in motility, sensory perception, and the life cycles of eukaryotes ranging from protists to humans. Despite the ubiquity and importance of these organelles, their composition is not well known. Here we use mass spectrometry to
Pazour, Gregory J. +3 more
openaire +3 more sources
Advanced Science, EarlyView.The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang +20 more
wiley +1 more source
Comparative Biology of Centrosomal Structures in Eukaryotes
Cells, 2018 The centrosome is not only the largest and most sophisticated protein complex within a eukaryotic cell, in the light of evolution, it is also one of its most ancient organelles.
Ralph Gräf
doaj +1 more source
The Cilium Secretes Bioactive Ectosomes [PDF]
Current Biology, 2013 The release of membrane vesicles from the surface of cells into their surrounding environment is now recognized as an important pathway for the delivery of proteins to extracellular sites of biological function. Membrane vesicles of this kind, termed exosomes and ectosomes, are the result of active processes and have been shown to carry a wide array of
Wood, Christopher R. +3 more
openaire +2 more sources