Results 81 to 90 of about 34,354 (355)
Biofilm Control by Active Topography with Mucin Coating
Advanced Functional Materials, EarlyView.This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han +4 more
wiley +1 more source
Autophagy and the primary cilium in cell metabolism: What’s upstream?
Frontiers in Cell and Developmental Biology, 2022 The maintenance of cellular homeostasis in response to extracellular stimuli, i.e., nutrient and hormone signaling, hypoxia, or mechanical forces by autophagy, is vital for the health of various tissues.
Aurore Claude-Taupin +2 more
doaj +1 more source
Internal friction controls active ciliary oscillations near the instability threshold [PDF]
Science Advances 6 (33), eabb0503 (2020), 2019 Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We show, in contrast, that external fluid friction is negligible compared to internal elastic stress through a ...
arxiv +1 more source
Microfluidic pumping using artificial magnetic cilia
, 2018 One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions.
Alexeev, Alexander +2 more
core +1 more source
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
Advanced Healthcare Materials, EarlyView.This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi +13 more
wiley +1 more source
The miR‐669a‐5p/G3BP/HDAC6/AKAP12 Axis Regulates Primary Cilia Length
Advanced SciencePrimary cilia are conserved organelles in most mammalian cells, acting as “antennae” to sense external signals. Maintaining a physiological cilium length is required for cilium function.
Weina Wang +6 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2023 Cancer whose major problems are metastasis, treatment resistance, and recurrence is the leading cause of death worldwide. Tumor-initiating stem cells (TiSCs) are a subset of the tumor population responsible for tumor resistance and relapse. Understanding
Babak Behnam +4 more
doaj +1 more source
Evaluating efficiency and robustness in cilia design [PDF]
Phys. Rev. E 93, 033119 (2016), 2015 Motile cilia are used by many eukaryotic cells to transport flow. Cilia-driven flows are important to many physiological functions, yet a deep understanding of the interplay between the mechanical structure of cilia and their physiological functions in healthy and diseased conditions remains elusive.
arxiv +1 more source
Probing cilia-driven flow in living embryos using femtosecond laser ablation and fast imaging [PDF]
, 2009 Embryonic development strictly depends on fluid dynamics. As a consequence, understanding biological fluid dynamic is essential since it is unclear how flow affects development.
Fraser, Scott E. +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling +4 more
wiley +1 more source