Results 31 to 40 of about 15,669 (253)

Determination of cilostazol and its active metabolite 3,4-dehydro cilostazol from small plasma volume by UPLC−MS/MS

open access: yesJournal of Pharmaceutical Analysis, 2015
A simple, rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC−MS/MS) method has been developed for the simultaneous determination of cilostazol and its pharmacologically active metabolite 3,4-dehydro cilostazol in
Nejal M. Bhatt   +5 more
doaj   +1 more source

The protective effect of cilostazol on isolated rabbit femoral arteries under conditions of ischemia and reperfusion: the role of the nitric oxide pathway

open access: yesClinics, 2012
OBJECTIVES: The clinical significance of ischemia/reperfusion of the lower extremities demands further investigation to enable the development of more effective therapeutic alternatives.
Mariana R.G.A. Santos   +5 more
doaj   +1 more source

Rationale and design of "Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)" study : A randomised trial modulating endogenous fibrinolysis in patients with acute coronary syndrome [PDF]

open access: yes, 2019
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Gorog, Diana A   +5 more
core   +2 more sources

5. THE EFFECT OF CILOSTAZOL TO ARTERIAL STIFFNESS IN THE HYPERTENSIVE PATIENT

open access: yesArtery Research, 2009
Background: Cilostazol is a potent antiplatelet agent that selectively inhibits phosphodiesterase III, and also it has beneficial effect to peripheral arterial disease, like intermittent claudication, by direct vasodilative action.
Jin Oh Na   +8 more
doaj   +1 more source

Effects of ischemic preconditioning and cilostazol on muscle ischemia-reperfusion injury in rats [PDF]

open access: yes, 2014
PURPOSE: To evaluate effects of ischemic preconditioning and Cilostazol on muscle ischemia-reperfusion injury.METHODS: Male Wistar rats were submitted to muscle ischemic and reperfusion injury (4h of the left common iliac artery occlusion followed by 1h ...
Frias Neto, Carlos Alberto da Silva   +4 more
core   +3 more sources

Cilostazol protects hepatocytes against alcohol-induced apoptosis via activation of AMPK pathway.

open access: yesPLoS ONE, 2019
Alcoholic liver disease (ALD) is a worldwide health problem and hepatocyte apoptosis has been associated with the development/progression of ALD. However, no definite effective pharmacotherapy for ALD is currently available.
Youn Ju Lee   +6 more
doaj   +1 more source

Efficacy of cilostazol on platelet reactivity and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: insights from a meta-analysis of randomised trials [PDF]

open access: yes, 2014
Background: Cilostazol overcomes high on-treatment platelet reactivity (HTPR) and reduces adverse cardiovascular (CV) outcomes after percutaneous coronary intervention (PCI).
Bangalore, Sripal   +6 more
core   +1 more source

Phosphodiesterase 3 inhibition and cough in elderly asthmatics [PDF]

open access: yes, 2005
Aims Cough is a common symptom of bronchial asthma, a chronic inflammatory airway disease. Recently, the therapeutic effects of selective phosphodiesterase (PDE) inhibitors have been focused on bronchial asthma. This study was designed to investigate the
20313645   +20 more
core   +2 more sources

New Therapeutic Approaches for Alzheimer’s Disease and Cerebral Amyloid Angiopathy [PDF]

open access: yes, 2014
Accumulating evidence has shown a strong relationship between Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), and cerebrovascular disease.
Masafumi Ihara, Satoshi Saito
core   +2 more sources

Positive chronotropic effects of theophylline and cilostazol in patients with symptomatic sick sinus syndrome who have declined permanent pacing [PDF]

open access: yesReviews in Cardiovascular Medicine, 2020
Pacemakers are more commonly recommended than theophylline for sick sinus syndrome (SSS) treatment. The positive effects of cilostazol on bradyarrhythmias also have been reported.
In Tae Jin, Namsik Yoon, Hyung Ki Jeong, Ki Hong Lee, Hyung Wook Park, Jeong Gwan Cho
doaj   +1 more source

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